// Workers AI · dad joke modeWhat did SOHLH2 gene say? I'm paired to help.

SOHLH2
Identifiers
Aliases	SOHLH2, SPATA28, TEB1, bHLHe81, spermatogenesis and oogenesis specific basic helix-loop-helix 2, SOSF2
External IDs	OMIM: 616066; GeneCards: SOHLH2; OMA:SOHLH2 - orthologs
Gene location (Human) Chr. Chromosome 13 (human) Band 13q13.3 Start 36,168,217 bp End 36,214,588 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte sperm testicle left testis gonad right testis muscle layer of sigmoid colon placenta nucleus accumbens prefrontal cortex n/a More reference expression data BioGPS n/a
Gene ontology Molecular function core promoter sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific protein dimerization activity DNA binding protein homodimerization activity protein heterodimerization activity DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus cytoplasm Biological process transcription by RNA polymerase II multicellular organism development oogenesis transcription, DNA-templated regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II spermatogenesis oocyte differentiation cell differentiation regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54937 n/a Ensembl ENSG00000120669 n/a UniProt Q9NX45 n/a RefSeq (mRNA) NM_017826 NM_001282147 n/a RefSeq (protein) NP_001269076 NP_060296 n/a Location (UCSC) Chr 13: 36.17 – 36.21 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Spermatogenesis and oogenesis specific basic helix-loop-helix 2 is a protein which in humans is encoded by the gene SOHLH2. Like its homolog, SOHLH1, this protein is a transcription factor which is involved in the regulation of spermatogenesis and oogenesis.