// Workers AI · dad joke modeWhat did OR6C2 say to its date? You're a gene-ius match.

OR6C2
Identifiers
Aliases	OR6C2, OR6C67, olfactory receptor family 6 subfamily C member 2
External IDs	MGI: 3030625; HomoloGene: 71950; GeneCards: OR6C2; OMA:OR6C2 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) Band 12q13.2 Start 55,444,069 bp End 55,453,347 bp
Gene location (Mouse) Chr. Chromosome 10 (mouse) Band 10|10 D3 Start 129,357,661 bp End 129,364,222 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve heart left ventricle salivary gland blood endometrium esophagus tibial nerve n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 341416 258932 Ensembl ENSG00000179695 ENSMUSG00000047626 UniProt Q9NZP2 Q8VGJ0 RefSeq (mRNA) NM_054105 NM_146930 RefSeq (protein) NP_473446 NP_667141 Location (UCSC) Chr 12: 55.44 – 55.45 Mb Chr 10: 129.36 – 129.36 Mb PubMed search
Wikidata
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Olfactory receptor 6C2 is a protein that in humans is encoded by the OR6C2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: Evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. Bibcode:2000PNAS...97.2870R. doi:10.1073/pnas.040580197. PMC 16022. PMID 10706615.
• Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12". Nature. 440 (7082): 346–51. Bibcode:2006Natur.440..346S. doi:10.1038/nature04569. PMID 16541075.

External links

• OR6C2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.