// Workers AI · dad joke modeWhy was OR5M11 sad? It had a gene-eral problem.

OR5M11
Identifiers
Aliases	OR5M11, OR11-199, olfactory receptor family 5 subfamily M member 11
External IDs	MGI: 3030863; HomoloGene: 73972; GeneCards: OR5M11; OMA:OR5M11 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11q12.1 Start 56,542,340 bp End 56,543,257 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 D Start 85,804,239 bp End 85,809,257 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in urinary bladder right testis Top expressed in ovary liver More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219487 258154 Ensembl ENSG00000255223 ENSMUSG00000059873 UniProt Q96RB7 A2ATE0 RefSeq (mRNA) NM_001005245 NM_001011852 RefSeq (protein) NP_001005245 NP_001011852 Location (UCSC) Chr 11: 56.54 – 56.54 Mb Chr 2: 85.8 – 85.81 Mb PubMed search
Wikidata
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Olfactory receptor 5M11 is a protein that in humans is encoded by the OR5M11 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5M11+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.