OR2A2

OR2A2
Identifiers
Aliases	OR2A2, OR2A17P, OR2A2P, OR7-11, OST008, olfactory receptor family 2 subfamily A member 2
External IDs	MGI: 3030271; HomoloGene: 133887; GeneCards: OR2A2; OMA:OR2A2 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) Band 7q35 Start 144,109,583 bp End 144,110,539 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6|6 B2.1 Start 43,140,216 bp End 43,146,795 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon ganglionic eminence muscle of thigh renal cortex Top expressed in spermatid More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity olfactory receptor activity G protein-coupled receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 442361 258293 Ensembl ENSG00000221989 ENSG00000285071 ENSMUSG00000071481 UniProt Q6IF42 Q8VEV1 RefSeq (mRNA) NM_001005480 NM_146296 RefSeq (protein) NP_001005480 NP_666408 Location (UCSC) Chr 7: 144.11 – 144.11 Mb Chr 6: 43.14 – 43.15 Mb PubMed search
Wikidata
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Olfactory receptor 2A2 is a protein that in humans is encoded by the OR2A2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR2A2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.