OR5B2

OR5B2
Identifiers
Aliases	OR5B2, OR11-240, OST073, olfactory receptor family 5 subfamily B member 2
External IDs	MGI: 3031285; HomoloGene: 133897; GeneCards: OR5B2; OMA:OR5B2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11q12.1 Start 58,421,238 bp End 58,428,121 bp
Gene location (Mouse) Chr. Chromosome 19 (mouse) Band 19|19 A Start 12,972,378 bp End 12,977,781 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Descending thoracic aorta coronary artery left coronary artery human musculoskeletal system skeletal muscle muscle of leg n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390190 258700 Ensembl ENSG00000172365 ENSMUSG00000046913 UniProt Q96R09 Q8VFX5 RefSeq (mRNA) NM_001005566 NM_146705 RefSeq (protein) NP_001005566 NP_666916 Location (UCSC) Chr 11: 58.42 – 58.43 Mb Chr 19: 12.97 – 12.98 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5B2 is a protein that in humans is encoded by the OR5B2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5B2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.