Oct-2

For the day, see October 2.

POU2F2
Identifiers
Aliases	POU2F2, OCT2, OTF2, Oct-2, POU class 2 homeobox 2
External IDs	OMIM: 164176; MGI: 101897; HomoloGene: 55674; GeneCards: POU2F2; OMA:POU2F2 - orthologs
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1HDP
Gene location (Human) Chr. Chromosome 19 (human) Band 19q13.2 Start 42,086,110 bp End 42,196,585 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7 A3|7 13.73 cM Start 24,786,769 bp End 24,879,151 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte buccal mucosa cell granulocyte lymph node pancreatic ductal cell paraflocculus of cerebellum blood vena cava frontal pole middle frontal gyrus Top expressed in zygote Olfactory peduncle pelvic ganglion secondary oocyte male urethra lumbar subsegment of spinal cord molecular layer of cerebellar cortex neural layer of retina epithelium of male urethra spleen More reference expression data BioGPS n/a
Gene ontology Molecular function DNA-binding transcription factor activity protein domain specific binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus cytoplasm nucleoplasm intracellular membrane-bounded organelle Biological process humoral immune response regulation of transcription, DNA-templated cell maturation positive regulation of transcription by RNA polymerase II positive regulation of transcription, DNA-templated transcription, DNA-templated mature B cell differentiation transcription by RNA polymerase II snRNA transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5452 18987 Ensembl ENSG00000028277 ENSMUSG00000008496 UniProt P09086 Q00196 RefSeq (mRNA) NM_001207025 NM_001207026 NM_001247994 NM_002698 NM_001393934 NM_001393935 NM_001393936 NM_001394376 NM_001394377 NM_001394378 NM_001163554 NM_001163555 NM_001163556 NM_011138 RefSeq (protein) NP_001193954 NP_001193955 NP_001234923 NP_002689 NP_001157026 NP_001157027 NP_001157028 NP_035268 Location (UCSC) Chr 19: 42.09 – 42.2 Mb Chr 7: 24.79 – 24.88 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

POU domain, class 2, transcription factor 2
Identifiers
Symbol	POU2F2
Alt. symbols	OTF2
NCBI gene	5452
HGNC	9213
OMIM	164176
RefSeq	NM_002698
UniProt	P09086
Other data
Locus	Chr. 19
Search for Structures Swiss-model Domains InterPro

Oct-2 (octamer-binding protein 2) also known as POU domain, class 2, transcription factor 2 is a protein that in humans is encoded by the POU2F2 gene.

Oct-2 is an octamer transcription factor which is a member of the POU family.

External links

• Octamer+Transcription+Factor-2 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• FactorBook POU2F2