COPZ1

COPZ1
Identifiers
Aliases	COPZ1, COPZ, HSPC181, zeta-COP, zeta1-COP, CGI-120, coatomer protein complex subunit zeta 1, COPI coat complex subunit zeta 1
External IDs	OMIM: 615472; MGI: 1929063; HomoloGene: 9366; GeneCards: COPZ1; OMA:COPZ1 - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HF6, 5A1U, 5A1V, 5A1W, 5A1X, 5A1Y
Gene location (Human)
Chr.	Chromosome 12 (human)
End	54,351,846 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	103,208,295 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; body of pancreas; ; ventricular zone; ; stromal cell of endometrium; ; ganglionic eminence; ; rectum; ; monocyte; ; right adrenal gland; ; gallbladder; ; smooth muscle tissue;
	Top expressed in
	yolk sac; ; dermis; ; duodenum; ; right kidney; ; epithelium of stomach; ; human fetus; ; jejunum; ; islet of Langerhans; ; neural tube; ; choroid plexus of fourth ventricle;
	More reference expression data
	More reference expression data
Orthologs
	22818
	56447
	ENSG00000111481
	ENSMUSG00000060992
	P61923
	P61924
	NM_001271734; NM_001271735; NM_001271736; NM_016057
	NM_019817; NM_001357748
	NP_001258663; NP_001258664; NP_001258665; NP_057141
	NP_062791; NP_001344677
	Wikidata
View/Edit Human	View/Edit Mouse

Coatomer subunit zeta-1 is a protein that in humans is encoded by the COPZ1 gene.^[5]

Interactions

COPZ1 has been shown to interact with COPG.^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000111481 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060992 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: COPZ1 coatomer protein complex, subunit zeta 1".
↑ Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (November 2000). "Identification and characterization of novel isoforms of COP I subunits". J. Biochem. 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392.
↑ Faulstich D, Auerbach S, Orci L, Ravazzola M, Wegchingel S, Lottspeich F, Stenbeck G, Harter C, Wieland FT, Tschochner H (Oct 1996). "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex" (PDF). J. Cell Biol. 135 (1): 53–61. doi:10.1083/jcb.135.1.53. PMC 2121028. PMID 8858162.

External links

Human COPZ1 genome location and COPZ1 gene details page in the UCSC Genome Browser.
Overview of all the structural information available in the PDB for UniProt: P61923 (Human Coatomer subunit zeta-1) at the PDBe-KB.

Pelham HR, Rothman JE (2000). "The debate about transport in the Golgi--two sides of the same coin?". Cell. 102 (6): 713–9. doi:10.1016/S0092-8674(00)00060-X. PMID 11030615. S2CID 18044044.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Pavel J, Harter C, Wieland FT (1998). "Reversible dissociation of coatomer: functional characterization of a beta/delta-coat protein subcomplex". Proc. Natl. Acad. Sci. U.S.A. 95 (5): 2140–5. Bibcode:1998PNAS...95.2140P. doi:10.1073/pnas.95.5.2140. PMC 19276. PMID 9482852.
Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (2001). "Identification and characterization of novel isoforms of COP I subunits". J. Biochem. 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000111481 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060992 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: COPZ1 coatomer protein complex, subunit zeta 1".

[pmid11056392-6] Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (November 2000). "Identification and characterization of novel isoforms of COP I subunits". J. Biochem. 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392.

[pmid8858162-7] Faulstich D, Auerbach S, Orci L, Ravazzola M, Wegchingel S, Lottspeich F, Stenbeck G, Harter C, Wieland FT, Tschochner H (Oct 1996). "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex" (PDF). J. Cell Biol. 135 (1): 53–61. doi:10.1083/jcb.135.1.53. PMC 2121028. PMID 8858162.

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COPZ1

Interactions

References

External links

Further reading