AP3B2

AP3B2
Identifiers
Aliases	AP3B2, NAPTB, adaptor related protein complex 3 beta 2 subunit, EIEE48, adaptor related protein complex 3 subunit beta 2, DEE48
External IDs	OMIM: 602166; MGI: 1100869; HomoloGene: 55837; GeneCards: AP3B2; OMA:AP3B2 - orthologs
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	81,143,673 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; Brodmann area 10; ; Brodmann area 9; ; cingulate gyrus; ; ganglionic eminence; ; amygdala; ; nucleus accumbens; ; hypothalamus; ; Region I of hippocampus proper; ; superior frontal gyrus;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; neural layer of retina; ; visual cortex; ; primary visual cortex; ; superior frontal gyrus; ; cerebellar cortex; ; supraoptic nucleus; ; dorsomedial hypothalamic nucleus; ; central gray substance of midbrain; ; facial motor nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	transporter activity;
Cellular component	AP-3 adaptor complex; membrane coat; cytoplasmic vesicle; clathrin-coated vesicle membrane; membrane; COPI-coated vesicle; axon cytoplasm; Golgi apparatus; intracellular vesicle;
Biological process	anterograde axonal transport; protein transport; anterograde synaptic vesicle transport; intracellular protein transport; vesicle-mediated transport; post-Golgi vesicle-mediated transport;
	Sources:Amigo / QuickGO
Orthologs
	8120
	11775
	n/a
	ENSMUSG00000062444
	Q13367
	Q9JME5
	NM_001278511; NM_001278512; NM_004644; NM_001348440; NM_001348441
	NM_021492; NM_146192
	NP_001265440; NP_001265441; NP_004635; NP_001335369; NP_001335370
	NP_067467
	Wikidata
View/Edit Human	View/Edit Mouse

AP-3 complex subunit beta-2 is a protein that in humans is encoded by the AP3B2 gene.^[4]^[5]^[6]

References

1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062444 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Newman LS, McKeever MO, Okano HJ, Darnell RB (Oct 1995). "Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein". Cell. 82 (5): 773–83. doi:10.1016/0092-8674(95)90474-3. PMID 7671305.
↑ Darnell RB, Furneaux HM, Posner JB (Jun 1991). "Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors". J Neurosci. 11 (5): 1224–30. doi:10.1523/JNEUROSCI.11-05-01224.1991. PMC 6575333. PMID 1851215.
↑ "Entrez Gene: AP3B2 adaptor-related protein complex 3, beta 2 subunit".

External links

Human AP3B2 genome location and AP3B2 gene details page in the UCSC Genome Browser.

Dell'Angelica EC, Ohno H, Ooi CE, et al. (1997). "AP-3: an adaptor-like protein complex with ubiquitous expression". EMBO J. 16 (5): 917–28. doi:10.1093/emboj/16.5.917. PMC 1169692. PMID 9118953.
Dell'Angelica EC, Klumperman J, Stoorvogel W, Bonifacino JS (1998). "Association of the AP-3 adaptor complex with clathrin". Science. 280 (5362): 431–4. Bibcode:1998Sci...280..431D. doi:10.1126/science.280.5362.431. PMID 9545220.
Lim DS, Kirsch DG, Canman CE, et al. (1998). "ATM binds to beta-adaptin in cytoplasmic vesicles". Proc. Natl. Acad. Sci. U.S.A. 95 (17): 10146–51. Bibcode:1998PNAS...9510146L. doi:10.1073/pnas.95.17.10146. PMC 21476. PMID 9707615.
Faundez VV, Kelly RB (2000). "The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform". Mol. Biol. Cell. 11 (8): 2591–604. doi:10.1091/mbc.11.8.2591. PMC 14942. PMID 10930456.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Dubois T, Zemlickova E, Howell S, Aitken A (2003). "Centaurin-alpha 1 associates in vitro and in vivo with nucleolin". Biochem. Biophys. Res. Commun. 301 (2): 502–8. doi:10.1016/S0006-291X(02)03010-3. PMID 12565890.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Chen C, Zou X, Ji C, et al. (2007). "Characterization of AP3B2_v2, a novel splice variant of human AP3B2". DNA Seq. 18 (3): 165–8. doi:10.1080/10425170600842121. PMID 17453999. S2CID 725773.

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[refGRCm38Ensembl-1] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062444 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7671305-4] Newman LS, McKeever MO, Okano HJ, Darnell RB (Oct 1995). "Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein". Cell. 82 (5): 773–83. doi:10.1016/0092-8674(95)90474-3. PMID 7671305.

[pmid1851215-5] Darnell RB, Furneaux HM, Posner JB (Jun 1991). "Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors". J Neurosci. 11 (5): 1224–30. doi:10.1523/JNEUROSCI.11-05-01224.1991. PMC 6575333. PMID 1851215.

[entrez-6] "Entrez Gene: AP3B2 adaptor-related protein complex 3, beta 2 subunit".

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This page was redesigned at the edge.

AP3B2

References

External links

Further reading