GPR148

GPR148
Identifiers
Aliases	GPR148, BTR, PGR6, G protein-coupled receptor 148
External IDs	HomoloGene: 131347; GeneCards: GPR148; OMA:GPR148 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2q21.1 Start 130,729,070 bp End 130,730,336 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans cerebellum cerebellar hemisphere right hemisphere of cerebellum pituitary gland anterior pituitary primary visual cortex Brodmann area 9 hypothalamus rectum n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process G protein-coupled receptor signaling pathway signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 344561 n/a Ensembl ENSG00000173302 n/a UniProt Q8TDV2 n/a RefSeq (mRNA) NM_207364 n/a RefSeq (protein) NP_997247 n/a Location (UCSC) Chr 2: 130.73 – 130.73 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

G protein-coupled receptor 148, also known as GPR148, is a human orphan receptor from GPCR superfamily. It is expressed primarily in nervous system and testis. Is may be implicated in prostate cancer.

Further reading

• Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. S2CID 7116392.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Parmigiani RB, Magalhães GS, Galante PA, et al. (2005). "A novel human G protein-coupled receptor is over-expressed in prostate cancer". Genet. Mol. Res. 3 (4): 521–31. PMID 15688318.
• Gloriam DE, Schiöth HB, Fredriksson R (2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochim. Biophys. Acta. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID 15777626.