Trepipam

Trepipam
Clinical data
Other names	SCH-12679; SCH12679
Identifiers
	IUPAC name (5R)-7,8-dimethoxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine;
CAS Number	56030-50-3;
PubChem CID	91277;
ChemSpider	4849;
UNII	8LMO6J899I;
Chemical and physical data
Formula	C19H23NO2
Molar mass	297.398 g·mol−1
3D model (JSmol)	Interactive image;
Specific rotation	+31.8°
Density	1.072 ± 0.06 g/cm3 (predicted)
Melting point	105–106 °C (221–223 °F) (experimental)
Boiling point	416.8 ± 45.0 °C (782.2 ± 81.0 °F) (predicted)
	SMILES CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)OC)OC;
	InChI InChI=1S/C19H23NO2/c1-20-10-9-15-11-18(21-2)19(22-3)12-16(15)17(13-20)14-7-5-4-6-8-14/h4-8,11-12,17H,9-10,13H2,1-3H3/t17-/m1/s1; Key:ICPHJSKVAZMKIV-QGZVFWFLSA-N;

Trepipam (INNTooltip International Nonproprietary Name; developmental code name SCH-12679) is a dopamine receptor agonist of the benzazepine group that was never marketed.^[1] It acts specifically as an agonist of the dopamine D₁ receptor.^[2] It is closed related structurally to fenoldopam, a peripherally acting selective D₁ receptor partial agonist which is used as an antihypertensive agent.

References

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