KIF9

KIF9
Identifiers
Aliases	KIF9, kinesin family member 9
External IDs	OMIM: 607910; MGI: 1098237; HomoloGene: 65620; GeneCards: KIF9; OMA:KIF9 - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3NWN
Gene location (Human)
Chr.	Chromosome 3 (human)
End	47,283,451 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	110,354,247 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; sperm; ; caput epididymis; ; left testis; ; mucosa of paranasal sinus; ; right testis; ; right uterine tube; ; olfactory zone of nasal mucosa; ; tendon of biceps brachii; ; corpus epididymis;
	Top expressed in
	spermatid; ; spermatocyte; ; seminiferous tubule; ; olfactory epithelium; ; choroid plexus of lateral ventricle; ; choroid plexus of fourth ventricle; ; Epithelium of choroid plexus; ; vestibular sensory epithelium; ; oocyte; ; primary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein dimerization activity; nucleotide binding; microtubule motor activity; protein binding; microtubule binding; ATP binding; ATPase activity;
Cellular component	cytoskeleton; vesicle; podosome; cytoplasm; kinesin complex; microtubule;
Biological process	extracellular matrix disassembly; regulation of podosome assembly; organelle disassembly; microtubule-based movement;
	Sources:Amigo / QuickGO
Orthologs
	64147
	16578
	ENSG00000088727
	ENSMUSG00000032489
	Q9HAQ2; Q6PJI1
	Q9WV04
NM_001134878; NM_022342; NM_182902; NM_182903; NM_001377474;
	NM_001377475; NM_001377476; NM_001377477
	NM_001163569; NM_010628
NP_001128350; NP_071737; NP_878905; NP_001364403; NP_001364404;
	NP_001364405; NP_001364406
	NP_001157041; NP_034758
	Wikidata
View/Edit Human	View/Edit Mouse

Kinesin family member 9 (KIF9), also known as kinesin-9, is a human protein encoded by the KIF9 gene. It is part of the kinesin family of motor proteins.

Function

The beating of the flagella in sperm is regulated by KIF9 activity.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000088727 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032489 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Miyata H, Shimada K, Morohoshi A, Oura S, Matsumura T, Xu Z, et al. (April 2020). "Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa". FASEB Journal. 34 (4): 5389–5400. doi:10.1096/fj.201902755R. PMC 7136151. PMID 32072696.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000088727 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032489 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[:0-5] Miyata H, Shimada K, Morohoshi A, Oura S, Matsumura T, Xu Z, et al. (April 2020). "Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa". FASEB Journal. 34 (4): 5389–5400. doi:10.1096/fj.201902755R. PMC 7136151. PMID 32072696.

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Function

References