KIF19

KIF19
Identifiers
Aliases	KIF19, KIF19A, kinesin family member 19
External IDs	MGI: 2447024; HomoloGene: 17709; GeneCards: KIF19; OMA:KIF19 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	74,355,820 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	114,681,565 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; sural nerve; ; olfactory zone of nasal mucosa; ; spleen; ; granulocyte; ; C1 segment; ; hypothalamus; ; amygdala; ; caudate nucleus; ; putamen;
	Top expressed in
	islet of Langerhans; ; spermatocyte; ; hypothalamus; ; testicle; ; lens; ; ovary; ; spermatid; ; embryo; ; morula; ; striatum of neuraxis;
	More reference expression data
	n/a
Gene ontology
Molecular function	microtubule binding; microtubule motor activity; nucleotide binding; ATPase activity; plus-end-directed microtubule motor activity; ATP binding;
Cellular component	cytoplasm; axoneme; cell projection; cilium; microtubule; cytoskeleton; kinesin complex;
Biological process	microtubule-based movement; axonemal microtubule depolymerization; plus-end specific microtubule depolymerization;
	Sources:Amigo / QuickGO
Orthologs
	124602
	286942
	ENSG00000196169
	ENSMUSG00000010021
	Q2TAC6
	Q99PT9
	NM_153209
	NM_001102615
	NP_694941
	NP_001096085
	Wikidata
View/Edit Human	View/Edit Mouse

Kinesin family member 19 (KIF19) is a protein in humans encoded by the KIF19 gene. It is part of the kinesin family of motor proteins.

Function

KIF19 is involved in cancer metastasis, as well as cell-cell and cell-matrix interactions.^[5]

1 2 3 GRCh38: Ensembl release 89: ENSG00000196169 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000010021 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Eisenberg, Samuel C.; Dey, Abhinav; Birnbaum, Rayna; Sharp, David J. (2020-09-04). "The kinesin-8 member Kif19 alters microtubule dynamics, suppresses cell adhesion, and promotes cancer cell invasion". bioRxiv 10.1101/2020.09.04.282657.

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