4-APB

4-APB
Clinical data
Other names	4-(2-Aminopropyl)benzofuran; 4-APB
Drug class	Serotonin–norepinephrine–dopamine releasing agent
Identifiers
	IUPAC name 1-(1-benzofuran-4-yl)propan-2-amine;
CAS Number	286834-83-1;
PubChem CID	10130546;
ChemSpider	8306061;
UNII	BXL47QK09N;
CompTox Dashboard (EPA)	DTXSID901043369 ;
Chemical and physical data
Formula	C11H13NO
Molar mass	175.231 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(CC1=C2C=COC2=CC=C1)N;
	InChI InChI=1S/C11H13NO/c1-8(12)7-9-3-2-4-11-10(9)5-6-13-11/h2-6,8H,7,12H2,1H3; Key:XROLBZOMVNMIFN-UHFFFAOYSA-N;

4-(2-Aminopropyl)benzofuran (4-APB) is a monoamine releasing agent and novel designer drug of the benzofuran family.^[3]^[4]^[5]^[2]^[1] It acts as a serotonin–norepinephrine–dopamine releasing agent (SNDRA).^[1]^[2] The drug was first detected, in Europe, by 2011.^[3]

References

1 2 3 Rickli A, Kopf S, Hoener MC, Liechti ME (July 2015). "Pharmacological profile of novel psychoactive benzofurans". Br J Pharmacol. 172 (13): 3412–3425. doi:10.1111/bph.13128. PMC 4500375. PMID 25765500.
1 2 3 Simmler LD, Liechti ME (2018). "Pharmacology of MDMA- and Amphetamine-Like New Psychoactive Substances". Handb Exp Pharmacol. Handbook of Experimental Pharmacology. 252: 143–164. doi:10.1007/164_2018_113. ISBN 978-3-030-10560-0. PMID 29633178.
1 2 "Europol 2011 Annual Report on the implementation of Council Decision 2005/387/JHA". Europol. 23 October 2018. Retrieved 27 February 2025.
↑ Stanczuk A, Morris N, Gardner EA, Kavanagh P (April 2013). "Identification of (2-aminopropyl)benzofuran (APB) phenyl ring positional isomers in internet purchased products". Drug Test Anal. 5 (4): 270–276. doi:10.1002/dta.1451. PMID 23349125.
↑ Casale JF, Hays PA (2012). "The characterization of 6-(2-aminopropyl) benzofuran and differentiation from its 4-, 5-, and 7-positional analogues" (PDF). Microgram Journal. 9 (2): 61–74.

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