Polythiazide

Polythiazide
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
MedlinePlus	a601101
ATC code	C03AA05 (WHO) ;
Identifiers
	IUPAC name 6-chloro-2-methyl-3-{[(2,2,2-trifluoroethyl)thio]methyl}-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;
CAS Number	346-18-9 ;
PubChem CID	4870;
IUPHAR/BPS	7274;
ChemSpider	4704 ;
UNII	36780APV5N;
KEGG	D00657 ;
ChEMBL	ChEMBL1587 ;
CompTox Dashboard (EPA)	DTXSID6025939 ;
ECHA InfoCard	100.005.881
Chemical and physical data
Formula	C11H13ClF3N3O4S3
Molar mass	439.87 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=S(C1=CC(S(=O)(N(C(CSCC(F)(F)F)N2)C)=O)=C2C=C1Cl)(N)=O;
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Polythiazide is a thiazide diuretic.^[1]^[2]

References

↑ O'Brien ET, MacKinnon J (October 1972). "Propranolol and polythiazide in treatment of hypertension". British Heart Journal. 34 (10): 1042–4. doi:10.1136/hrt.34.10.1042. PMC 458544. PMID 5086971.
↑ Monroy A, Plata C, Hebert SC, Gamba G (July 2000). "Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: a new model for ions and diuretics interaction". American Journal of Physiology. Renal Physiology. 279 (1): F161-9. doi:10.1152/ajprenal.2000.279.1.f161. PMID 10894798.

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v t e Symporter inhibitors
Na⁺-Cl⁻	Thiazides: Bendroflumethiazide Chlorothiazide Cyclopenthiazide Cyclothiazide Hydrochlorothiazide Hydroflumethiazide Methyclothiazide Polythiazide Trichlormethiazide; Others: Chlortalidone (chlorthalidone) Metolazone
Na⁺-K⁺-Cl⁻	Bumetanide Furosemide
See also: Receptor/signaling modulators