Etocyanozene

Etocyanozene
Identifiers
	IUPAC name 1-[2-(diethylamino)ethyl]-2-[(4-ethoxyphenyl)methyl]benzimidazole-5-carbonitrile;
CAS Number	15419-87-1;
PubChem CID	27269;
ChemSpider	25380;
Chemical and physical data
Formula	C23H28N4O
Molar mass	376.504 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCN(CC)CCN1C2=C(C=C(C=C2)C#N)N=C1CC3=CC=C(C=C3)OCC;
	InChI InChI=1S/C23H28N4O/c1-4-26(5-2)13-14-27-22-12-9-19(17-24)15-21(22)25-23(27)16-18-7-10-20(11-8-18)28-6-3/h7-12,15H,4-6,13-14,16H2,1-3H3; Key:SMNJGNKSTXLJSY-UHFFFAOYSA-N;

Etocyanozene (etocyanazene, 5-cyano-etodesnitazene) is a benzimidazole opioid 'desnitazene' derivative with opioid effects. It was first developed in the 1950s as part of the research that led to better-known compounds such as etonitazene. It is an analogue of etonitazene where the 5-nitro (NO₂) group has been replaced by a nitrile (C≡N) group.^[1] It is described as having "reduced but still significant" potency compared to etonitazene itself.^[2] It was made illegal in Germany in July 2021.^[3]

References

↑ Lecolier S, Trouiller G (1967). "Nouveaux benzimidazoles doués d'activité morphinique" [New benzimidazoles with opioid activity.]. Chim. Ther. (in French). 2: 16–24.
↑ "A review of the evidence on the use and harms of 2-benzyl benzimidazole ('nitazene') and piperidine benzimidazolone ('brorphine-like') opioids" (PDF). UK: Advisory Council on the Misuse of Drugs. July 2022.
↑ "Anhang - Zweite Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes" [Appendix - Second regulation amending the appendix to the New Psychoactive Substances Act]. Gesetze und Verordnungen des deutschen Bundesrechts im Internet [Laws and regulations of German federal law on the Internet] (in German).

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[1] Lecolier S, Trouiller G (1967). "Nouveaux benzimidazoles doués d'activité morphinique" [New benzimidazoles with opioid activity.]. Chim. Ther. (in French). 2: 16–24.

[2] "A review of the evidence on the use and harms of 2-benzyl benzimidazole ('nitazene') and piperidine benzimidazolone ('brorphine-like') opioids" (PDF). UK: Advisory Council on the Misuse of Drugs. July 2022.

[3] "Anhang - Zweite Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes" [Appendix - Second regulation amending the appendix to the New Psychoactive Substances Act]. Gesetze und Verordnungen des deutschen Bundesrechts im Internet [Laws and regulations of German federal law on the Internet] (in German).

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Etocyanozene

See also

References