DUSP13A
| DUSP13A | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | DUSP13A, dual specificity phosphatase 13A, BEDP, MDSP, DUSP13 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | GeneCards: DUSP13A | |||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Dual specificity protein phosphatase 13A is an enzyme that in humans is encoded by the DUSP13A gene.[2] This gene has previously been considered part of DUSP13, but that term includes the related gene, DUSP13B.[3] This protein has also been called "muscle-restricted dual-specificity phosphatase" (MDSP) to distinguish it from DUSP13B, which has been called "Testis- and skeletal-muscle-specific phosphatase" or "TMDP".[4][5]
Function
[edit]Members of the protein tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This gene encodes a dual specificity phosphatase that acts on both phosphotyrosine and phosphoserine/threonine residues. The encoded protein is expressed in skeletal muscle.[2]
References
[edit]
This article incorporates public domain material from websites or documents of the National Institutes of Health.- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- 1 2 "DUSP13A dual specificity phosphatase 13A [ Homo sapiens (human) ]". Retrieved 2026-08-11.
- ↑ "DUSP13B dual specificity phosphatase 13B [ Homo sapiens (human) ]". Retrieved 2026-08-11.
- ↑ Park JE, Park BC, Kim HA, Song M, Park SG, Lee DH, Kim HJ, Choi HK, Kim JT, Cho S (August 2010). "Positive regulation of apoptosis signal-regulating kinase 1 by dual-specificity phosphatase 13A" (PDF). Cellular and molecular life sciences. 67 (15): 2619–2629. doi:10.1007/s00018-010-0353-3.
- ↑ "Q6B8I1 · DS13A_HUMAN". UniProt consortium. Retrieved 2026-08-11.
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