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R6372

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From Wikipedia, the free encyclopedia

R6372
Identifiers
  • 8-[1-(4-methylphenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC22H27N3O
Molar mass349.478 g·mol−1
3D model (JSmol)
  • CC1=CC=C(C=C1)C(C)N2CCC3(CC2)C(=O)NCN3C4=CC=CC=C4
  • InChI=1S/C22H27N3O/c1-17-8-10-19(11-9-17)18(2)24-14-12-22(13-15-24)21(26)23-16-25(22)20-6-4-3-5-7-20/h3-11,18H,12-16H2,1-2H3,(H,23,26)
  • Key:MBCUBRXUURKNCY-UHFFFAOYSA-N

R6372 is a potent opioid analgesic drug from the spiropiperidine family, related to opioid designer drugs such as spirochlorphine. It has around 186x the potency of morphine, making it approximately twice the potency of fentanyl.[1]

See also

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References

[edit]
  1. ↑ Humblet C, Burnotte C, Evrard G, Durant F (1978-12-01). "8-[1-(4-Methylphenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 0.5 methanol:R6372". Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 34 (12): 3830–3832. Bibcode:1978AcCrB..34.3830H. doi:10.1107/S0567740878012388.
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