Edge Rewrite
// HTMLRewriter · presentation

This page was redesigned at the edge.

Cloudflare fetched the original article and streamed it through HTMLRewriter to apply an entirely new visual system without rebuilding the source page.

// request.cf · coarse context

A page that knows where it met you.

Only coarse request metadata is shown. This demo does not display or persist visitor IP addresses.

Country
US
Cloudflare location
CMH
Connection
HTTP/2
Language
Not provided

Ray ID: a418dbaa2d67984a

Jump to content

// Workers AI · dad joke modeWhat did Adamantyl-HHC say? I'm bonded to you.

From Wikipedia, the free encyclopedia

Adamantyl-HHC
Identifiers
  • (6aR,10aR)-6,6,9-trimethyl-3-(1-adamantyl)-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
Chemical and physical data
FormulaC26H36O2
Molar mass380.572 g·mol−1
3D model (JSmol)
  • CC1(C)Oc2cc(cc(O)c2[C@@H]2CC(C)CC[C@H]21)C12CC3CC(CC(C3)C2)C1

Adamantyl-HHC is a drug that is a cannabinoid agonist, and has been sold as a designer drug. It is closely related to AM-411 (adamantyl-Δ8-THC) but with the saturated ring system found in hexahydrocannabinol (HHC) and related compounds. While AM-411 and numerous other derivatives with adamantyl or similar substituents replacing the pentyl side chain have been reported in the scientific literature,[1][2][3][4][5] adamantyl-HHC itself does not appear to have been previously reported prior to its appearance as a designer drug in 2026. It is one of a number of novel compounds from the "classical" cannabinoid group structurally related to THC which have appeared following bans on previously legal semi-synthetic derivatives such as Δ8-THC and HHC, and has been added to the list of controlled drugs in several jurisdictions such as Hungary, Czech Republic and Turkey.[6][7][8][9][10]

See also

[edit]

References

[edit]
  1. ↑ Lu D, Meng Z, Thakur GA, Fan P, Steed J, Tartal CL, et al. (14 July 2005). "Adamantyl cannabinoids: a novel class of cannabinergic ligands". Journal of Medicinal Chemistry. 48 (14): 4576–4585. doi:10.1021/jm058175c. PMID 15999995.
  2. ↑ Dixon DD, Sethumadhavan D, Benneche T, Banaag AR, Tius MA, Thakur GA, et al. (12 August 2010). "Heteroadamantyl cannabinoids". Journal of Medicinal Chemistry. 53 (15): 5656–5666. doi:10.1021/jm100390h. PMC 3699191. PMID 20593789.
  3. ↑ Ho TC, Tius MA, Nikas SP, Tran NK, Tong F, Zhou H, et al. (15 April 2021). "Oxa-adamantyl cannabinoids". Bioorganic & Medicinal Chemistry Letters. 38 127882. doi:10.1016/j.bmcl.2021.127882. PMID 33636308.
  4. ↑ Liddle I, Glass M, Tyndall JD, Vernall AJ (4 April 2022). "Covalent cannabinoid receptor ligands - structural insight and selectivity challenges". RSC Medicinal Chemistry. 13 (5): 497–510. doi:10.1039/d2md00006g. PMC 9132230. PMID 35694688.
  5. ↑ Docampo-Palacios ML, Ramirez GA, Tesfatsion TT, Okhovat A, Pittiglio M, Ray KP, et al. (4 September 2023). "Saturated Cannabinoids: Update on Synthesis Strategies and Biological Studies of These Emerging Cannabinoid Analogs". Molecules. 28 (17). Basel, Switzerland: 6434. doi:10.3390/molecules28176434. PMC 10490552. PMID 37687263.
  6. ↑ AIPSIN. "679. Адамантил-гексагидроканнабинол (adamantyl-HHC). АИПСИН, 2026". АИПСИН.
  7. ↑ Balázs B (2026-08-21). "Rajzfilmfigurás tasakban hozza a posta a kábítószert a fiataloknak". Index.
  8. ↑ Sárosi P (2026-07-08). "18 ÚJ SZER Kerül Tiltólistára: de ELÉG-E a Tiltás?". Drogriporter.
  9. ↑ "Társadalmi egyeztetés az új pszichoaktív anyagok szabályozásáról". kormany.hu.
  10. ↑ "BAZI Maddeleri̇n 2313 Sayili Uyuşturucu Maddeleri̇n Murakabesi̇ Hakkinda Kanun Hükümleri̇ne Tabi̇ Tutulmasi Hakkinda Karar. Karar Sayısı: 11684. 31.08.2026 Tarih Ve 33356 Sayılı R.G." www.pcgumruk.com.