2-Cl-HHC
| Identifiers | |
|---|---|
| |
| Chemical and physical data | |
| Formula | C21H31ClO2 |
| Molar mass | 350.93 g·mol−1 |
| 3D model (JSmol) | |
| |
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2-Cl-HHC (2-chloro-hexahydrocannabinol) is a chlorinated derivative of hexahydrocannabinol which has been sold as a designer drug, and is presumed to have cannabinoid activity. It was first identified as a component of a cannabinoid e-cigarette liquid in Japan in 2025 which was represented as being free from illicit cannabinoids such as THC. The active ingredient instead was identified as a mixture of 2-Cl-HHC and 4-Cl-HHC along with 2,4-dichloro-HHC and trace amounts of other chlorinated phytocannabinoid derivatives, as well as the ester Δ9-THCB-O-butanoate.[1] While chlorinated derivatives of THC such as 9-Cl-HHC had previously been identified, their biological activity has not been studied.[2] 2-Cl-HHC has since been added to the controlled drugs list in Hungary.[3][4]


See also
[edit]References
[edit]- ↑ Tanaka R, Kawamura M, Ito M, Kikura-Hanajiri R (November 2025). "Identification of Novel THC Analogs: Chloro Derivatives of Hexahydrocannabinol and Tetrahydrocannabibutol Butanoate in an Oil Product Obtained in Japan". Drug Testing and Analysis. 17 (11): 2170–2177. doi:10.1002/dta.3927. PMID 40880172.
- ↑ Banijamali AR, Van Der Schyf CJ, Makriyannis A (February 1998). "Addition and elimination of HCl to tetrahydrocannabinol isomers. A method for the preparation of stereospecifically 2H‐labeled cannabinoids". Journal of Labelled Compounds and Radiopharmaceuticals. 41 (2): 121–130.
- ↑ Sárosi P (2026-07-08). "18 ÚJ SZER Kerül Tiltólistára: de ELÉG-E a Tiltás?". Drogriporter.
- ↑ "Társadalmi egyeztetés az új pszichoaktív anyagok szabályozásáról". kormany.hu.