USP51

USP51
Identifiers
Aliases	USP51, ubiquitin specific peptidase 51
External IDs	MGI: 3588217; GeneCards: USP51
Enzyme activity
Gene location (Human)
Chr.	X chromosome (human)
End	55,489,848 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	151,792,412 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; caput epididymis; ; gonad; ; bronchial epithelial cell; ; retinal pigment epithelium; ; tail of epididymis; ; testicle; ; endothelial cell; ; buccal mucosa cell; ; mucosa of paranasal sinus;
	Top expressed in
	yolk sac; ; secondary oocyte; ; morula; ; zygote; ; embryo; ; primary oocyte; ; embryo; ; epiblast; ; placenta; ; ventricular zone;
	More reference expression data
	n/a
Gene ontology
Molecular function	thiol-dependent deubiquitinase; zinc ion binding; peptidase activity; cysteine-type peptidase activity; hydrolase activity; metal ion binding; chromatin binding; histone binding;
Cellular component	chromosome;
Biological process	protein deubiquitination; ubiquitin-dependent protein catabolic process; proteolysis; histone deubiquitination; regulation of response to DNA damage stimulus; regulation of cell cycle process; regulation of double-strand break repair via homologous recombination; regulation of double-strand break repair via nonhomologous end joining; DNA repair; cellular response to DNA damage stimulus;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	158880
	635253
	ENSG00000247746
	ENSMUSG00000067215
	Q70EK9
	B1AY15
	NM_201286
	NM_001137547
	NP_958443
	NP_001131019
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 51 is an enzyme that in humans is encoded by the USP51 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000247746 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000067215 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.
↑ "Entrez Gene: USP51 ubiquitin specific peptidase 51".

Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Puente XS, López-Otín C (2004). "A genomic analysis of rat proteases and protease inhibitors". Genome Res. 14 (4): 609–22. doi:10.1101/gr.1946304. PMC 383305. PMID 15060002.
Xie H, Diber A, Pollock S, et al. (2004). "Bridging expressed sequence alignments through targeted cDNA sequencing". Genomics. 83 (4): 572–6. doi:10.1016/j.ygeno.2003.07.003. PMID 15028280.
Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, et al. (2004). "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases". Biochem. Biophys. Res. Commun. 314 (1): 54–62. Bibcode:2004BBRC..314...54Q. doi:10.1016/j.bbrc.2003.12.050. PMID 14715245.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000247746 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000067215 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12838346-5] Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.

[entrez-6] "Entrez Gene: USP51 ubiquitin specific peptidase 51".

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USP51

References

Further reading