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Topopyrone C

From Wikipedia, the free encyclopedia
Topopyrone C
Names
Preferred IUPAC name
5,9,11-Trihydroxy-2-methyl-4H-anthra[1,2-b]pyran-4,7,12-trione
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
  • InChI=1S/C18H10O7/c1-6-2-10(20)15-12(22)5-9-14(18(15)25-6)17(24)13-8(16(9)23)3-7(19)4-11(13)21/h2-5,19,21-22H,1H3
    Key: AWDAPFGGFWZKGB-UHFFFAOYSA-N
  • CC1=CC(=O)C2=C(C=C3C(=C2O1)C(=O)C4=C(C=C(C=C4C3=O)O)O)O
Properties
C18H10O7
Molar mass 338.271 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Topopyrone C and its analogs are fungal isolates with anticancer activity in vitro.[2]

References

[edit]
  1. "KNApSAcK Metabolite Information - C00015651". www.knapsackfamily.com.
  2. Ishiyama, D; Kanai, Y; Senda, H; Iwatani, W; Iwatani, W; Konno, H; Kanazawa, S (2000). "Novel human topoisomerase I inhibitors, topopyrones A, B, C and D. II. Structure elucidation". The Journal of Antibiotics. 53 (9): 873–8. doi:10.7164/antibiotics.53.873. PMID 11099219.