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Tipredane

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From Wikipedia, the free encyclopedia
Tipredane
Clinical data
Other namesSQ-27239; 17α-(Ethylthio)-9α-fluoro-11β-hydroxy-20-thiapregn-1,4-diene-3-one; 17α-(Ethylthio)-9α-fluoro-11β-hydroxy-17-(methylthio)androsta-1,4-dien-3-one
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • (8S,9R,10S,11S,13S,14S,17R)-17-Ethylsulfanyl-9-fluoro-11-hydroxy-10,13-dimethyl-17-methylsulfanyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H31FO2S2
Molar mass410.61 g·mol−1
3D model (JSmol)
  • CCS[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)SC
  • InChI=1S/C22H31FO2S2/c1-5-27-21(26-4)11-9-16-17-7-6-14-12-15(24)8-10-19(14,2)22(17,23)18(25)13-20(16,21)3/h8,10,12,16-18,25H,5-7,9,11,13H2,1-4H3/t16-,17-,18-,19-,20-,21+,22-/m0/s1
  • Key:DXEXNWDGDYUITL-FXSSSKFRSA-N

Tipredane (developmental code name SQ-27239) is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2]

References

[edit]
  1. ↑ Rainsford KD, Velo GP (6 December 2012). New Developments in Antirheumatic Therapy. Springer Science & Business Media. pp. 154, 164. ISBN 978-94-009-1253-3.
  2. ↑ Korting HC, Schafer-Korting M (24 July 1998). The Benefit/Risk Ratio: A Handbook for the Rational Use of Potentially Hazardous Drugs. CRC Press. pp. 363–. ISBN 978-1-4398-0591-6.


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