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Talk:Trimethylaminuria

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Treatment

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The following comment by Adanna78 was moved from Trimethylaminuria#Treatment

Should include how much of each supplements should be taken and also who do you get in contact with for more information.

- 2/0 (cont.) 22:57, 17 September 2010 (UTC)Reply

Deleted section

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The Incidence section I just deleted was lifted almost word-for-word, without attribution, from an ABC News Website. That's plagiarism. Preceding unsigned comment added by J M Rice (talkcontribs) 19:07, 29 March 2012 (UTC)Reply

Wow

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I just landed here from a link from outside, read the lead, and didn't understand a word. -Roxy the dog™ (resonate) 03:29, 25 March 2015 (UTC)Reply

1/1000 1/10000?

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When you say rare, say how rare. Jidanni (talk) 01:41, 13 January 2018 (UTC)Reply

Found this: The frequency of the severe type of the disorder in this population could thus be as high as 1 in 40,000. The true prevalence of the disorder is unknown; however, of patients referred to a malodour clinic in Philadelphia, 35% had trimethylaminuria. The incidence of heterozygous carriers is higher in other ethnic groups studied: 1.7% in Jordanian, 3.8% in Ecuadorian and 11.0% in New Guinean populations,20 suggesting the frequency of the disorder may be as high as 1 in 3000 and 1 in 400 in the latter two groups, respectively. https://www.nature.com/articles/ejhg2011214#:~:text=The%20frequency%20of%20the%20severe,Philadelphia%2C%2035%25%20had%20trimethylaminuria. --Brutalar (talk) 07:10, 6 September 2022 (UTC)Reply

Needs some metabolic pathway descriptions

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Article would be better with a clear definition of the life cycle of tma in the body. A section about precursors, bacteria in the gut, direct tmao from seafood, etc. Also maybe move a bit of stuff from symptoms as I didn't have a good spot to put it.

I'll see if I can do something over the next few days. Brutalar (talk) 21:38, 8 September 2022 (UTC)Reply

Remove References to Chlorophyllin Treatment "Study"

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The Wikipedia article on Chlorophyllin states that it is primarily notable as an "alternative medicine" treatment for a vague set of bad odors from metabolically unrelated causes. It was a fad over-the-counter supplement, that has largely been proven ineffective. The article further relates that the hype surrounding chlorophyllin's medical uses was so overblown that it could reasonably be considered a "hoax."

Let's not perpetuate a hoax! Especially one that's already documented as such in Wikipedia!

https://en.wikipedia.org/wiki/Chlorophyllin 1MathematicalGuy (talk) 08:07, 20 January 2025 (UTC)Reply

Hello, if you are interested you might want to check for reliable sources on Chlorophyllin : Moribundum (talk) 19:11, 20 January 2025 (UTC)Reply
"Sequestering of trimethylamine produced in the gut. When taken as dietary supplements, activated charcoal (750 mg 2x/day for 10 days) and copper chlorophyllin (60 mg 3x/day after meals for 3 weeks) decrease the concentration of free trimethylamine in the urine [Yamazaki et al 2004]."
It might be notable to mention Moribundum (talk) 19:12, 20 January 2025 (UTC)Reply