Talk:Taxadiene synthase

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Latest comment: 14 years ago1 comment1 person in discussion

Taxadiene synthase, the largest of terpene cyclases, is the enzyme catalyzes the rate-limiting step of toxoids biosynthesis. It can help to converts the geranylgeranyl diphosphate (GGPP) to taxa-4,11-diene, the starting compound of more than 500 kinds of taxanes in yew tree. Taxanes can help the plant to fight against the predation of animals, mechanical damage, and many other kinds scenarios that not good for its growth or development. Taxadiene synthase contains the conserved metal-binding motifs and requires Mg2+ for optimal catalytic activity, belongs to class I terpenoid cyclase. — Preceding unsigned comment added by 129.49.21.125 (talk) 04:04, 26 January 2012 (UTC)Reply

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