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Talk:Protriptyline

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"Unique among the TCAs, protriptyline tends to be energizing instead of sedating, and it is sometimes used in narcolepsy to achieve a wakefulness-promoting effect."

How is it different from desipramine and nortriptyline, since all 3 have similar high sert/net affinities. Nuklear (talk) 07:52, 5 July 2009 (UTC)Reply

"indicated for ADHD" - cannot find a substantiating source anywhere

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I cannot find a substantiating original source for this claim. The FDA pamphlet indexed on google does not mention ADHD as an approved indication. Statspearls echoes this claim but links to a study that refers to protriptyline as an investigational agent. I will double check at a later date and remove this claim from the article if others do not have any input to the contrary.

https://www.ncbi.nlm.nih.gov/books/NBK499828/ Oro Temp (talk) 22:29, 22 May 2025 (UTC)Reply