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Talk:Orotic acid

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Untitled

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not enough info. mention:

1) orotic acid is an intermediate in pyrimidine synthesis (C, T)

2) multi-organ tumour promoter

74.111.2.51 02:10, 11 December 2006 (UTC) Prof. Larry Moran, PhD. University of Toronto, Department of BiochemistryReply


Wrong Lemma

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It's not pyrimidinecarboxylic acid, the systematic name is 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid or uracil-6-carboxylic acid, but orotic acid is more common. -- 217.224.70.151 13:09, 26 July 2006 (UTC)Reply

Vitamin?

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The article states that "...it is not a vitamin, but is instead manufactured in the body by intestinal flora." By that definition, vitamin K wouldn't be a vitamin. --ἀνυπόδητος (talk) 11:39, 31 July 2009 (UTC)Reply

Vitamin K is available via microbial action, but some humans still need supplements. Bearian (talk) 16:11, 2 October 2014 (UTC)Reply

Orotic Acid Mutagen?

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There is no proper citation of the rather serious claim that Orotic Acid, a necessary nutrient for humans to live, is a mutagenic compound. A google search pulled up nothing except a few abstracts about 5-Fluoro-Orotic Acid, a different compound altogether. — Preceding unsigned comment added by 65.190.21.85 (talk) 00:23, 26 December 2013 (UTC)Reply

A Google search on 12/27/2014 turned up a materials safety data sheet for orotic acid, anhydrous (1,2,3,6-Tetrahydro-2,6-dioxo-4- pyrimidinecarboxylic Acid; 6-Uracilcarboxylic Acid) from ScienceLab.com that states: "Chronic Effects on Humans: MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/ or yeast." [1] Also found this substance listed as having an RTECS class of Mutagen. [2]

References

Tricreatine orotate

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This article has been proposed for deletion. However, otherwise non-notable salts of an acid should be merged into the parent article when feasible. Bearian (talk) 16:12, 2 October 2014 (UTC)Reply

 Done. The tricreatine orotate article was at best poorly sourced, but I claim no expertise in this area. Hopefully someone with a greater knowledge of chemistry can provide a decent source for the merged content. Euryalus (talk) 12:45, 11 October 2014 (UTC)Reply

Pronunciation

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Because of the unfortunate name of B¹³, I propose the correct pronunciation be added to the article to prevent confusion. 68.185.117.66 (talk) 15:04, 6 November 2022 (UTC)Reply

Well it is an acid with a rather funny name, but the correct way to say it is Or-ot-ic acid. I have no idea of how to use the IPA system.If someone can transscribe the name it would be a great help. Cadmium (talk) 10:34, 7 February 2023 (UTC)Reply

"Pyrimidinecarboxylic acid" listed at Redirects for discussion

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The redirect Pyrimidinecarboxylic acid has been listed at redirects for discussion to determine whether its use and function meets the redirect guidelines. Readers of this page are welcome to comment on this redirect at Wikipedia:Redirects for discussion/Log/2025 August 21 § Pyrimidinecarboxylic acid until a consensus is reached. Marbletan (talk) 19:13, 21 August 2025 (UTC)Reply