Talk:Linoleic acid
Add topicLatest comment: 6 months ago by ເສລີພາບ in topic F. Sacc, chemist of mystery
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Science March 2025 study suggests link with certain types of breast cancer
[edit]https://doi.org/10.1126/science.adm9805
This isn't my field so an expert should probably take a closer look. Jefferson.tan (talk) 23:06, 18 April 2025 (UTC)
- Very weak and unreliable study done on rats, as the study says itself "we demonstrated the relevance of this FABP5-mTORC1 signaling pathway in vivo by feeding animals a diet enriched for safflower oil that promoted TNBC tumor growth". The source fails WP:MEDRS. There is no clinical data showing that linoleic acid increases cancer risk. Veg Historian (talk) 00:18, 19 April 2025 (UTC)
- Thanks for comment and requesting a review, as cancerogenic effect is life threatening if confirmed! ~ Xobbitua (talk) 07:30, 22 April 2025 (UTC)
- Pretty much everything gives rat-susceptible rats cancer. It is of no relevance to human health. Bon courage (talk) 07:35, 22 April 2025 (UTC)
- PS note that again for TNBC specific https://pubmed.ncbi.nlm.nih.gov/40080571/ Xobbitua (talk) 17:41, 22 April 2025 (UTC)
- As stated that is a weak paper that fails our WP:MEDRS guidelines. There is no human outcome data to support that connection. If linoleic acid causes cancer in humans we would have known this a long time ago because we have plenty of tissue level data. They have measured tissue levels of linoleic acid in long-term epidemiolocal studies and there are no negative health outcomes. . Veg Historian (talk) 18:01, 22 April 2025 (UTC)
- Thanks for comment and requesting a review, as cancerogenic effect is life threatening if confirmed! ~ Xobbitua (talk) 07:30, 22 April 2025 (UTC)
F. Sacc, chemist of mystery
[edit]The article currently discusses F. Sacc linked to "Fritz Sacc". I do not know who this could be. My best guess is F. Sacc is actually Frédéric Sacc (1819–1890) who studied agricultural chemistry. I have changed the link to just be F. Sacc. ເສລີພາບ (talk) 22:45, 26 January 2026 (UTC)