Spirobrorphine

Spirobrorphine
Identifiers
	IUPAC name 8-[1-(4-bromophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;
PubChem CID	177864517;
ChemSpider	133330325;
Chemical and physical data
Formula	C21H24BrN3O
Molar mass	414.347 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C1=CC=C(C=C1)Br)N2CCC3(CC2)C(=O)NCN3C4=CC=CC=C4;
	InChI InChI=1S/C21H24BrN3O/c1-16(17-7-9-18(22)10-8-17)24-13-11-21(12-14-24)20(26)23-15-25(21)19-5-3-2-4-6-19/h2-10,16H,11-15H2,1H3,(H,23,26); Key:BKVHJNVMUACENG-UHFFFAOYSA-N;

Spirobrorphine is a synthetic opioid chemical compound which has been sold as a designer drug, first reported in the USA in February 2026.^[1] It was added to the controlled drug schedules in Canada in June 2026.^[2] Its pharmacology has not yet been studied but it is believed to be a potent opioid narcotic in a similar manner to related compounds such as spirochlorphine and R6372.

References

↑ "Emerging Global Synthetic Opioid Threats: Benzimidazol-2-ones – The Orphines. Colombo Plan Health Alert, February 2026" (PDF). www.cfsre.org.
↑ "Order Amending Schedule V to the Controlled Drugs and Substances Act (R 29676, Spirobrorphine and Spirochlorphine): SOR/2026-71. Canada Gazette, Part II, Volume 160, Number 9. 17 April 2026". gazette.gc.ca. Government of Canada, Public Works and Government Services Canada, Integrated Services Branch, Canada Gazette.

[1] "Emerging Global Synthetic Opioid Threats: Benzimidazol-2-ones – The Orphines. Colombo Plan Health Alert, February 2026" (PDF). www.cfsre.org.

[2] "Order Amending Schedule V to the Controlled Drugs and Substances Act (R 29676, Spirobrorphine and Spirochlorphine): SOR/2026-71. Canada Gazette, Part II, Volume 160, Number 9. 17 April 2026". gazette.gc.ca. Government of Canada, Public Works and Government Services Canada, Integrated Services Branch, Canada Gazette.

[1]

[2]

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Spirobrorphine

See also

References