Septin-14

SEPTIN14
Identifiers
Aliases	SEPTIN14, septin 14, SEPT14
External IDs	OMIM: 612140; MGI: 1921472; GeneCards: SEPTIN14
Gene location (Human)
Chr.	Chromosome 7 (human)
End	55,862,755 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	129,785,576 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; gonad; ; testicle; ; blood; ; monocyte; ; endometrium; ; anterior pituitary; ; right lobe of liver; ; spleen;
	Top expressed in
	zygote; ; spermatocyte; ; secondary oocyte; ; spermatid; ; primary oocyte; ; testicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity; molecular adaptor activity;
Cellular component	cytoplasm; cytoskeleton; septin ring; microtubule cytoskeleton; septin complex; septin filament array;
Biological process	cell cycle; cell division; mitotic cytokinesis; septin ring assembly; cilium assembly; cytoskeleton-dependent cytokinesis;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	346288
	74222
	ENSG00000154997
	ENSMUSG00000034219
	Q6ZU15
	Q9DA97
	NM_207366
	NM_028826
	NP_997249
	NP_083102
	Wikidata
View/Edit Human	View/Edit Mouse

Septin-14 is a protein that in humans is encoded by the SEPTIN14 gene (previously SEPT14).^[5]

Function

SEPT14 is a member of the highly conserved septin family of GTP-binding cytoskeletal proteins implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis, and other cellular functions.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000154997 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034219 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Septin 14".

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Septin-14

Function

References

Further reading