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Schisandrin

From Wikipedia, the free encyclopedia

Schisandrins [1] (schizandrins) are a group of bioactive chemical compounds found in Schisandra rubriflora, Schisandra sphenanthera, and Schisandra chinensis.[2][3] Schizandrin is a lignan.[4]

Schisandrin
Schisandrin. IUPAC [5] Name: 3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaen-9-ol

IUPAC Name*

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3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaen-9-ol *Computed by Lexichem TK 2.7.0 (PubChem release 2021.05.07)

CAS Common Chemistry

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7432-28-2[6][7][8]

Molecular Formula

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Molecular Weight

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432.5

PubChem CID

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23915[9]

Characteristics

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Schisandra chinensis (S. chinensis) berries were originally a component of traditional herbal medicine in China, Korea, and other east Asian countries.[citation needed]

Examples include:

Chemical structures of schisandrins A-C

References

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  1. "WikiData".
  2. Park, SY; Park, SJ; Park, TG; Rajasekar, S; Lee, SJ; Choi, YW (2013). "Schizandrin C exerts anti-neuroinflammatory effects by upregulating phase II detoxifying/antioxidant enzymes in microglia". International Immunopharmacology. 17 (2): 415–26. doi:10.1016/j.intimp.2013.06.032. PMID 23859871.
  3. "LOTUS - the natural products occurrence database".
  4. Ehambarampillai, D.; Wan, M. L. (2025). "A comprehensive review of Schisandra chinensis lignans: pharmacokinetics, pharmacological mechanisms, and future prospects in disease prevention and treatment". Chinese Medicine. 20 (1): 47. doi:10.1186/s13020-025-01096-z. PMC 11984061. PMID 40205412.
  5. "PubChem \ United States National Library of Medicine".
  6. "CAS Common Chemistry".
  7. "EPA DSSTox". Archived from the original on March 27, 2023.
  8. "European Chemicals Agency (ECHA)".
  9. "PubChem CID \ United States National Library of Medicine".