Repirinast

Repirinast
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 3-methylbutyl 7,8-dimethyl-4,5-dioxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-2-carboxylate;
CAS Number	73080-51-0 ;
PubChem CID	5050;
ChemSpider	4874 ;
UNII	4K8KA8B61G;
KEGG	D01890 ;
CompTox Dashboard (EPA)	DTXSID10223349 ;
Chemical and physical data
Formula	C20H21NO5
Molar mass	355.390 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=C(C2=C(C=C1)C3=C(C(=O)C=C(O3)C(=O)OCCC(C)C)C(=O)N2)C;
	InChI InChI=1S/C20H21NO5/c1-10(2)7-8-25-20(24)15-9-14(22)16-18(26-15)13-6-5-11(3)12(4)17(13)21-19(16)23/h5-6,9-10H,7-8H2,1-4H3,(H,21,23) ; Key:NFQIAEMCQGTTIR-UHFFFAOYSA-N ;
	(what is this?) (verify)

Repinirast (INN; marketed under the tradename Romet) is an antihistamine.^[1]^[2]

References

↑ Yamada N, Ohgaki M, Muramatsu M (1993). "Repirinast inhibits antigen-induced early and late pulmonary responses and airway hyperresponsiveness in guinea pigs". International Archives of Allergy and Immunology. 100 (4): 367–72. doi:10.1159/000236440. PMID 8386963.
↑ Yamada N, Kadowaki S, Takahashi K, Umezu K (September 1992). "MY-1250, a major metabolite of the anti-allergic drug repirinast, induces phosphorylation of a 78-kDa protein in rat mast cells". Biochemical Pharmacology. 44 (6): 1211–3. doi:10.1016/0006-2952(92)90387-x. PMID 1358073.

External links

Product information from Antia Laboratories Inc.

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[1] Yamada N, Ohgaki M, Muramatsu M (1993). "Repirinast inhibits antigen-induced early and late pulmonary responses and airway hyperresponsiveness in guinea pigs". International Archives of Allergy and Immunology. 100 (4): 367–72. doi:10.1159/000236440. PMID 8386963.

[2] Yamada N, Kadowaki S, Takahashi K, Umezu K (September 1992). "MY-1250, a major metabolite of the anti-allergic drug repirinast, induces phosphorylation of a 78-kDa protein in rat mast cells". Biochemical Pharmacology. 44 (6): 1211–3. doi:10.1016/0006-2952(92)90387-x. PMID 1358073.

[1]

[2]

v t e Antihistamines (R06)
Benzimidazoles (*)	Astemizole Azelastine Bilastine Emedastine Mizolastine Talastine
Diarylmethanes	Diarylmethoxyalkylamines: Bromazine (bromodiphenhydramine) Carbinoxamine Chlorphenoxamine Clemastine Diphenhydramine (+naproxen) Diphenylpyraline Doxylamine Ebastine Orphenadrine Diphenylmethanolpiperidines: Fexofenadine Terfenadine Diphenylmethylpiperazines: Buclizine Cetirizine Levocetirizine Chlorcyclizine Cinnarizine Cyclizine Etodroxizine Hydroxyzine Meclizine Oxatomide Phenylpyridinylpropanamines: Brompheniramine Chlorphenamine Dexbrompheniramine (+pseudoephedrine) Dexchlorpheniramine (+betamethasone) Pheniramine Others: Acrivastine Bamipine Dimetindene Phenyltoloxamine Pyrrobutamine Quifenadine Triprolidine
Ethylenediamines	Antazoline Chloropyramine Histapyrrodine Mepyramine (pyrilamine) Methapyrilene Phenbenzamine Thenalidine Tripelennamine (pyribenzamine)
Tricyclics	Dibenzocycloheptenes: Antidepressants (e.g., amitriptyline) Azatadine Cyproheptadine Deptropine Desloratadine Ketotifen Loratadine Rupatadine Phenothiazines: Alimemazine Fenethazine Hydroxyethylpromethazine Isothipendyl Mequitazine Methdilazine Oxomemazine Promethazine Others: Antidepressants (e.g., doxepin, mirtazapine, trimipramine) Epinastine Latrepirdine Mebhydrolin Olopatadine Perlapine Phenindamine Pimethixene
Others	Phenylpiperazines: Antidepressants (e.g., trazodone) Phenbenzamine
For topical use	Bamipine Chloropyramine Chlorphenoxamine Clemastine Dimetindene Diphenhydramine Doxepin Isothipendyl Mepyramine (pyrilamine) Promethazine

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References

External links