RERG

RERG
Identifiers
Aliases	RERG, RAS like estrogen regulated growth inhibitor
External IDs	OMIM: 612664; MGI: 2665139; HomoloGene: 50026; GeneCards: RERG; OMA:RERG - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ATV
Enzyme activity
Gene location (Human)
Chr.	Chromosome 12 (human)
End	15,348,675 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	137,147,495 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; tail of epididymis; ; body of uterus; ; synovial joint; ; Achilles tendon; ; left uterine tube; ; caput epididymis; ; myometrium; ; saphenous vein; ; synovial membrane;
	Top expressed in
	adrenal gland; ; facial motor nucleus; ; umbilical cord; ; molar; ; lumbar subsegment of spinal cord; ; dentate gyrus of hippocampal formation granule cell; ; body of femur; ; calvaria; ; conjunctival fornix; ; left lung lobe;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; GDP binding; estrogen receptor binding; GTPase activity;
Cellular component	cytosol; nucleus; membrane; cytoplasm; plasma membrane;
Biological process	negative regulation of cell population proliferation; response to hormone; negative regulation of cell growth; signal transduction; small GTPase mediated signal transduction; Ras protein signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	85004
	232441
	ENSG00000134533
	ENSMUSG00000030222
	Q96A58
	Q8R367
	NM_001190726; NM_032918
	NM_001164212; NM_001164214; NM_181988
	NP_001177655; NP_116307
	NP_001157684; NP_001157686; NP_871788
	Wikidata
View/Edit Human	View/Edit Mouse

RAS-like, estrogen-regulated, growth inhibitor is a protein in humans that is encoded by the RERG gene.^[5]

RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009].

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000134533 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030222 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: RAS-like, estrogen-regulated, growth inhibitor". Retrieved 2012-11-09.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Ras-related and estrogen-regulated growth inhibitor (RERG)

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RERG

References

External links

Further reading