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Phanquinone

From Wikipedia, the free encyclopedia
Phanquinone
Names
Other names
4,7-phenanthroline-5,6-dione
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.001.378 Edit this at Wikidata
EC Number
  • 201-516-0
365810
KEGG
UNII
  • InChI=1S/C12H6N2O2/c15-11-9-7(3-1-5-13-9)8-4-2-6-14-10(8)12(11)16/h1-6H
    Key: VLPADTBFADIFKG-UHFFFAOYSA-N
  • O=C3c1ncccc1c2c(nccc2)C3=O
Properties
C12H6N2O2
Molar mass 210.192 g·mol−1
Appearance yellow solid
Melting point 295 °C (563 °F; 568 K)
Hazards
GHS labelling:
GHS07: Exclamation mark
Warning
H302, H312, H332, H412
P261, P264, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Phanquinone is an organic compound with the formula C12H6N2O2. It is derived by oxidation of 4,7-phenanthroline.

It has been investigated as both antiprotozoal agent and for its bactericidal activity .[1] It has an extensive role as a ligand in coordination chemistry.[2][3]

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References

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  1. Mett H, Gyr K, Zak O, Vosbeck K (July 1984). "Duodeno-pancreatic secretions enhance bactericidal activity of antimicrobial drugs". Antimicrob. Agents Chemother. 26 (1): 35–8. doi:10.1128/aac.26.1.35. PMC 179912. PMID 6236746.
  2. Eckert, Timothy S.; Bruice, Thomas C. (1983). "Chemical properties of phenanthrolinequinones and the mechanism of amine oxidation by o-quinones of medium redox potentials". Journal of the American Chemical Society. 105 (13): 4431–4441. Bibcode:1983JAChS.105.4431E. doi:10.1021/ja00351a049.
  3. Ksenofontov, Vadim; Gaspar, Ana B.; Niel, Virginie; Reiman, Sergey; Real, José A.; Gütlich, Philipp (2004). "On the Nature of the Plateau in Two-Step Dinuclear Spin-Crossover Complexes". Chemistry – A European Journal. 10 (5): 1291–1298. doi:10.1002/chem.200305275. PMID 15007819.