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Orungo virus

From Wikipedia, the free encyclopedia
Orungo virus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Duplornaviricota
Class: Resentoviricetes
Order: Reovirales
Family: Sedoreoviridae
Genus: Orbivirus
Species:
Orbivirus orungoense
A microscopic photo of a molecule of Orungo Virus

Orungo virus (ORUV) is an arbovirus of the genus Orbivirus and the family Sedoreoviridae. There are four known subtypes of Orungo virus designated Orungo-1 (ORUV-1), Orungo-2 (ORUV-2), Orungo-3 (ORUV-3), and Orungo-4 (ORUV-4).[1] It was first isolated by the Uganda Virus Research Institute in Entebbe, Uganda by Oyewale Tomori[2] and colleagues on the 14th August, 1984.[3] Antibodies to the virus have been found in humans, monkeys, sheep, and cattle.[4] The virus is inactivated at temperatures of 37oC and above and is stable in a pH range of 5.0-7.0.[5]

Symptoms

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The disease is a febrile disease that has had over 60 reported cases which have caused the following symptoms: fever; headache; myalgia; vomiting and conjunctival inflammation.[3]

Geographical distribution

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The virus itself has been found in patients in Uganda, Nigeria, the Central African Republic, Senegal and the Ivory Coast.[3] However antigens for the disease have also been detected in Sierra Leone, but the virus has not been yet.[3]

References

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  1. "Virus Taxonomy: 2011 Release". International Committee on Virus Taxonomy. 2011. Archived from the original on 2016-03-03. Retrieved 2012-11-07.
  2. Tomori, O.; Fabiyi, A.; Murphy, F. (1976-01-01). "Characterization of Orungo virus, an orbivirus from Uganda and Nigeria". Archives of Virology. 51 (4): 285–298. doi:10.1007/bf01317932. ISSN 0304-8608. PMID 973798. S2CID 874348.
  3. 1 2 3 4 "ArboCat Virus: Orungo (ORUV)". wwwn.cdc.gov. Archived from the original on 2026-01-03. Retrieved 2026-06-01.
  4. Tomori O, Fabiyi A (September 1976). "Neutralizing antibodies to Orungo virus in man and animals in Nigeria". Tropical and Geographical Medicine. 28 (3): 233–8. PMID 827036.
  5. Tomori, O.; Fabiyi, A. (March 1977). "Orungo virus, an orbivirus from Africa: effects of physical and chemical agents". African Journal of Medicine and Medical Sciences. 6 (1): 33–38. ISSN 0309-3913. PMID 24332.