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NUFIP2

From Wikipedia, the free encyclopedia

NUFIP2
Identifiers
AliasesNUFIP2, 182-FIP, 82-FIP, FIP-82, PIG1, FMR1 interacting protein 2, nuclear FMR1 interacting protein 2, NUFP2
External IDsOMIM: 609356; MGI: 1915814; HomoloGene: 10808; GeneCards: NUFIP2; OMA:NUFIP2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020772

NM_001024205

RefSeq (protein)

NP_065823
NP_065823.1

NP_001019376

Location (UCSC)Chr 17: 29.26 – 29.29 MbChr 11: 77.58 – 77.63 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nuclear fragile X mental retardation-interacting protein 2 is a protein that in humans is encoded by the NUFIP2 gene.[5][6][7]

Interactions

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NUFIP2 has been shown to interact with FMR1 and Roquin-1.[8][5]

References

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  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000108256 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037857 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 Bardoni B, Castets M, Huot ME, Schenck A, Adinolfi S, Corbin F, Pastore A, Khandjian EW, Mandel JL (Jul 2003). "82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization". Hum Mol Genet. 12 (14): 1689–98. doi:10.1093/hmg/ddg181. PMID 12837692.
  6. Ramos A, Hollingworth D, Adinolfi S, Castets M, Kelly G, Frenkiel TA, Bardoni B, Pastore A (Jan 2006). "The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction". Structure. 14 (1): 21–31. doi:10.1016/j.str.2005.09.018. PMID 16407062.
  7. "Entrez Gene: NUFIP2 nuclear fragile X mental retardation protein interacting protein 2".
  8. Rehage N (2018). "Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA". Nature Communications. 9 (1): 299. Bibcode:2018NatCo...9..299R. doi:10.1038/s41467-017-02582-1. PMC 5775257. PMID 29352114.

Further reading

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