MicroRNA 425

MicroRNA 425 is a microRNA that in humans is encoded by the MIR425 gene.

Further reading

• Liang D, Meyer L, Chang DW, Lin J, Pu X, Ye Y, Gu J, Wu X, Lu K (December 2010). "Genetic variants in MicroRNA biosynthesis pathways and binding sites modify ovarian cancer risk, survival, and treatment response". Cancer Res. 70 (23): 9765–76. doi:10.1158/0008-5472.CAN-10-0130. PMC 5373101. PMID 21118967.
• Di Leva G, Piovan C, Gasparini P, Ngankeu A, Taccioli C, Briskin D, Cheung DG, Bolon B, Anderlucci L, Alder H, Nuovo G, Li M, Iorio MV, Galasso M, Santhanam R, Ramasamy S, Marcucci G, Perrotti D, Powell KA, Bratasz A, Garofalo M, Nephew KP, Croce CM (2013). "Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status". PLOS Genet. 9 (3) e1003311. doi:10.1371/journal.pgen.1003311. PMC 3591271. PMID 23505378.
• Arora P, Wu C, Khan AM, Bloch DB, Davis-Dusenbery BN, Ghorbani A, Spagnolli E, Martinez A, Ryan A, Tainsh LT, Kim S, Rong J, Huan T, Freedman JE, Levy D, Miller KK, Hata A, Del Monte F, Vandenwijngaert S, Swinnen M, Janssens S, Holmes TM, Buys ES, Bloch KD, Newton-Cheh C, Wang TJ (August 2013). "Atrial natriuretic peptide is negatively regulated by microRNA-425". J. Clin. Invest. 123 (8): 3378–82. doi:10.1172/JCI67383. PMC 3726159. PMID 23867623.
• Ma J, Liu J, Wang Z, Gu X, Fan Y, Zhang W, Xu L, Zhang J, Cai D (February 2014). "NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction". Mol. Cancer. 13: 40. doi:10.1186/1476-4598-13-40. PMC 3941686. PMID 24571667.
• Peng WZ, Ma R, Wang F, Yu J, Liu ZB (March 2014). "Role of miR-191/425 cluster in tumorigenesis and diagnosis of gastric cancer". Int J Mol Sci. 15 (3): 4031–48. doi:10.3390/ijms15034031. PMC 3975382. PMID 24603541.
• Moskwa P, Zinn PO, Choi YE, Shukla SA, Fendler W, Chen CC, Lu J, Golub TR, Hjelmeland A, Chowdhury D (December 2014). "A functional screen identifies miRs that induce radioresistance in glioblastomas". Mol. Cancer Res. 12 (12): 1767–78. doi:10.1158/1541-7786.MCR-14-0268. PMC 4386891. PMID 25256711.
• Liu P, Hu Y, Ma L, Du M, Xia L, Hu Z (October 2015). "miR-425 inhibits melanoma metastasis through repression of PI3K-Akt pathway by targeting IGF-1". Biomed. Pharmacother. 75: 51–7. doi:10.1016/j.biopha.2015.08.010. PMID 26463631.
• Zhang Y, Hu X, Miao X, Zhu K, Cui S, Meng Q, Sun J, Wang T (February 2016). "MicroRNA-425-5p regulates chemoresistance in colorectal cancer cells via regulation of Programmed Cell Death 10". J. Cell. Mol. Med. 20 (2): 360–9. doi:10.1111/jcmm.12742. PMC 4727563. PMID 26647742.
• Liu L, Zhao Z, Zhou W, Fan X, Zhan Q, Song Y (November 2015). "Enhanced Expression of miR-425 Promotes Esophageal Squamous Cell Carcinoma Tumorigenesis by Targeting SMAD2". J Genet Genomics. 42 (11): 601–611. doi:10.1016/j.jgg.2015.09.010. PMID 26674378.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.