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Methyl caffeate

From Wikipedia, the free encyclopedia
Methyl caffeate
Chemical structure of methyl caffeate
Names
Preferred IUPAC name
Methyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Other names
Caffeic acid methyl ester
methylcaffeate
Methyl 3,4-dihydroxycinnamate
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.236.052 Edit this at Wikidata
UNII
  • InChI=1S/C10H10O4/c1-14-10(13)5-3-7-2-4-8(11)9(12)6-7/h2-6,11-12H,1H3/b5-3+
    Key: OCNYGKNIVPVPPX-HWKANZROSA-N
  • InChI=1/C10H10O4/c1-14-10(13)5-3-7-2-4-8(11)9(12)6-7/h2-6,11-12H,1H3/b5-3+
    Key: OCNYGKNIVPVPPX-HWKANZROBE
  • COC(=O)/C=C/C1=CC(=C(C=C1)O)O
Properties
C10H10O4
Molar mass 194.186 g·mol−1
Related compounds
Related compounds
Caffeic acid, Ethyl caffeate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Methyl caffeate is an ester of caffeic acid, a naturally occurring phenolic compound. It is an α-glucosidase inhibitor.[1] Its physical form is a powder.

Natural occurrences

[edit]

Methyl caffeate can be found in the fruit of Solanum torvum.[2]

Health effect

[edit]

Methyl caffeate shows an antidiabetic effect in streptozotocin-induced diabetic rats.[2]

References

[edit]
  1. Takahashi, Keisuke; Yoshioka, Yasuyuki; Kato, Eisuke; Katsuki, Shigeki; Iida, Osamu; Hosokawa, Keizo; Kawabata, Jun (2014). "Methyl Caffeate as an α-Glucosidase Inhibitor from Solanum torvum Fruits and the Activity of Related Compounds". Bioscience, Biotechnology, and Biochemistry. 74 (4): 741–745. doi:10.1271/bbb.90789. hdl:2115/53430. PMID 20378981. S2CID 23067847.
  2. 1 2 Gandhi, Gopalsamy Rajiv; Ignacimuthu, Savarimuthu; Paulraj, Michael Gabriel; Sasikumar, Ponnusamy (2011). "Antihyperglycemic activity and antidiabetic effect of methyl caffeate isolated from Solanum torvum Swartz. Fruit in streptozotocin induced diabetic rats". European Journal of Pharmacology. 670 (2–3): 623–631. doi:10.1016/j.ejphar.2011.09.159. PMID 21963451.