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Methade

From Wikipedia, the free encyclopedia
Methade
Names
Preferred IUPAC name
N,N-Dimethyl-4,4-diphenylheptan-2-amine
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C21H29N/c1-5-16-21(17-18(2)22(3)4,19-12-8-6-9-13-19)20-14-10-7-11-15-20/h6-15,18H,5,16-17H2,1-4H3
    Key: MCFVCWVAZLRHPN-UHFFFAOYSA-N
  • CN(C(CC(CCC)(C1=CC=CC=C1)C2=CC=CC=C2)C)C
Properties
C21H29N
Molar mass 295.470 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Methade, or 6-(dimethylamino)-4,4-diphenylheptane, is the parent compound of the methadone and methadol series of opioid analgesics:[1]

Chemical derivatives

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The methade series includes the following compounds:

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Some related compounds include:

References

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  1. Perrine TD, May EL (1954). "Synthesis of 6-dimethylamino-4,4-diphenyl-heptane and other compounds related to methadone". Journal of Organic Chemistry. 19 (5): 773–779. doi:10.1021/jo01370a012. ISSN 1520-6904.