L-165041

L-165041
Clinical data
Pregnancy; category	N/A;
Legal status
Legal status	Investigational;
Identifiers
	IUPAC name [4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]acetic acid;
CAS Number	79558-09-1;
PubChem CID	6603901;
IUPHAR/BPS	2691;
DrugBank	DB08078;
ChemSpider	5036209;
UNII	7RV682Z3FQ;
CompTox Dashboard (EPA)	DTXSID6040745 ;
Chemical and physical data
Formula	C22H26O7
Molar mass	402.443 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCc1c(ccc(c1O)C(=O)C)OCCCOc2ccc(cc2)OCC(=O)O;
	InChI InChI=1S/C22H26O7/c1-3-5-19-20(11-10-18(15(2)23)22(19)26)28-13-4-12-27-16-6-8-17(9-7-16)29-14-21(24)25/h6-11,26H,3-5,12-14H2,1-2H3,(H,24,25); Key:HBBVCKCCQCQCTJ-UHFFFAOYSA-N;

L-165041 is a phenyloxyacetate PPARδ receptor agonist. It is less potent and PPARδ selective than GW 501516.^[2]

References

↑ Iwashita A, Muramatsu Y, Yamazaki T, Muramoto M, Kita Y, Yamazaki S, et al. (March 2007). "Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo". The Journal of Pharmacology and Experimental Therapeutics. 320 (3): 1087–96. doi:10.1124/jpet.106.115758. PMID 17167170. S2CID 9595370.
↑ Atta-ur-Rahman, Reitz AB (2005). Frontiers in Medicinal Chemistry, Volume 2. Bentham Science Publishers. pp. 244–. ISBN 978-1-608-05205-9. Retrieved 2 April 2013.

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