Jedi1

Jedi1
Names
	Preferred IUPAC name 2-methyl-5-phenylfuran-3-carboxylic acid
Identifiers
CAS Number	108124-17-0 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:194898;
ChEMBL	ChEMBL5208985;
ChemSpider	643637;
EC Number	673-051-5;
PubChem CID	736516;
CompTox Dashboard (EPA)	DTXSID30353051 ;
	InChI InChI=1S/C12H10O3/c1-8-10(12(13)14)7-11(15-8)9-5-3-2-4-6-9/h2-7H,1H3,(H,13,14) Key: VLMNACSEESRUAK-UHFFFAOYSA-N;
	SMILES CC1=C(C=C(O1)C2=CC=CC=C2)C(=O)O;
Properties
Chemical formula	C12H10O3
Molar mass	202.209 g·mol−1
Hazards
	GHS labelling:
Pictograms	‹ The template below (GHS corrosion) is being considered for merging with GHS pictogram. See templates for discussion to help reach a consensus. › ‹ The template below (GHS exclamation mark) is being considered for merging with GHS pictogram. See templates for discussion to help reach a consensus. ›
Signal word	Warning
Hazard statements	H315, H319, H335
Precautionary statements	P260, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Jedi1 (IUPAC name: 2-methyl-5-phenylfuran-3-carboxylic acid) is a chemical compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception.^[1]^[2]

References

↑ Wang Y, Chi S, Guo H, Li G, Wang L, Zhao Q, et al. (April 2018). "A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel". Nature Communications. 9 (1): 1300. Bibcode:2018NatCo...9.1300W. doi:10.1038/s41467-018-03570-9. PMC 5880808. PMID 29610524.
↑ Fang XZ, Zhou T, Xu JQ, Wang YX, Sun MM, He YJ, Pan SW, Xiong W, Peng ZK, Gao XH, Shang Y (January 2021). "Structure, kinetic properties and biological function of mechanosensitive Piezo channels". Cell & Bioscience. 11 (1): 13. doi:10.1186/s13578-020-00522-z. PMC 7796548. PMID 33422128.

This pharmacology-related article is a stub. You can help Wikipedia by adding missing information.

[1] Wang Y, Chi S, Guo H, Li G, Wang L, Zhao Q, et al. (April 2018). "A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel". Nature Communications. 9 (1): 1300. Bibcode:2018NatCo...9.1300W. doi:10.1038/s41467-018-03570-9. PMC 5880808. PMID 29610524.

[Fang_2021-2] Fang XZ, Zhou T, Xu JQ, Wang YX, Sun MM, He YJ, Pan SW, Xiong W, Peng ZK, Gao XH, Shang Y (January 2021). "Structure, kinetic properties and biological function of mechanosensitive Piezo channels". Cell & Bioscience. 11 (1): 13. doi:10.1186/s13578-020-00522-z. PMC 7796548. PMID 33422128.

[1]

[2]

This page was redesigned at the edge.

Jedi1

See also

References