Indoline
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| Names | |
|---|---|
| Preferred IUPAC name
2,3-Dihydro-1H-indole | |
| Other names
2,3-Dihydroindole | |
| Identifiers | |
3D model (JSmol) |
|
| 111915 | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.007.107 |
| EC Number |
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| 27284 | |
PubChem CID |
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| RTECS number |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C8H9N | |
| Molar mass | 119.16 g/mol |
| Appearance | Clear colourless liquid |
| Density | 1.063 g/mL |
| Melting point | −21 °C (−6 °F; 252 K) |
| Boiling point | 220 to 221 °C (428 to 430 °F; 493 to 494 K) |
| Hazards | |
| Flash point | 92.8 °C (199.0 °F; 365.9 K) |
| Safety data sheet (SDS) | Fisher Scientific |
| Related compounds | |
Related aromatics |
carbazole, indole, isoindoline, oxindole |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Indoline is an aromatic heterocyclic organic compound with the chemical formulation C8H9N. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing ring. The compound is based on the indole structure, but the 2-3 bond is saturated. By oxidation/dehydrogenation it can be converted to indole.[1][2]
Indoline can be produced from the reaction of indole, zinc and 85% phosphoric acid.[3] It was used to make Indocaine.
References
[edit]- ↑ Katritzky, A. R.; Pozharskii, A. F. (2000). Handbook of Heterocyclic Chemistry (2nd ed.). Academic Press. ISBN 0080429882.
- ↑ Clayden, J.; Greeves, N.; Warren, S.; Wothers, P. (2001). Organic Chemistry. Oxford, Oxfordshire: Oxford University Press. ISBN 0-19-850346-6.
- ↑ Dolby, Lloyd J.; Gribble, Gordon W. (1966). "A convenient preparation of indoline". Journal of Heterocyclic Chemistry. 3 (2): 124–125. doi:10.1002/jhet.5570030202. ISSN 0022-152X.
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