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Hyclate

From Wikipedia, the free encyclopedia

A hyclate (Latin: hyclas) is a pharmaceutical term for hydrochloride hemiethanolate hemihydrate[1][2] (·HCl·⁠1/2⁠EtOH·⁠1/2⁠H2O), e.g. doxycycline hyclate.[3][4]

References

[edit]
  1. ↑ "hyclate". The Free Dictionary. Retrieved 5 June 2018.
  2. ↑ Legendre, Alexandre O.; Silva, Laila R. R.; Silva, Douglas M.; Rosa, Iara M. L.; Azarias, Lilian C.; de Abreu, Polyana J.; de Araújo, Magali B.; Neves, Person P.; Torres, Claudia; Martins, Felipe T.; Doriguetto, Antonio C. (2012). "Solid state chemistry of the antibiotic doxycycline: structure of the neutral monohydrate and insights into its poor water solubility". CrystEngComm. 14 (7): 2532–2540. doi:10.1039/C1CE06181J.
  3. ↑ "Doxycycline hyclate – Final text to replace published monograph in The International Pharmacopoeia" (PDF). who.int. Retrieved 5 June 2018.
  4. ↑ Note: As of June 2018, doxycycline hyclate is apparently the only known, or used hyclate.
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