HLA-B59
major histocompatibility complex (human), class I, B59 | ||
| Alleles | B*5901 | |
| Structure (See HLA-B) | ||
| Symbol(s) | HLA-B | |
| EBI-HLA | B*5901 | |
| Locus | chr.6 6p21.31 | |
HLA-B59 (B59) is an HLA-B serotype. The serotype identifies the more common HLA-B*## gene products.[1] B59 is a hybrid between B*55 and B*51.[2] B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: HLA-serotype tutorial)
Serotype
[edit]| B*59 | B59 | Other | Sample |
| allele | % | % | size (N) |
| 5901 | 45 | 41 | 123 |
B*5901 allele frequencies
[edit]| freq | ||
| ref. | Population | (%) |
| [4] | Okinawan (USA Hawaii) | 6.3 |
| [4] | Japan (2) | 2.7 |
| [4] | Tarialan Khoton (Mongolia) | 2.4 |
| [4] | South Korea (3) | 2.1 |
| [4] | Gipuscoa Basque (Spain) | 2.0 |
| [4] | Japan Central | 1.8 |
| [4] | Casablanca (Morocco) | 1.8 |
| [4] | Hyogo (Japan) | 1.6 |
| [4] | N. Korean (Harbin, China) | 1.0 |
| [4] | Manchu (Harbin, China) | 0.6 |
| [4] | Naxi (Yunnan, China) | 0.6 |
| [4] | Girona (Catalonia, Spain) | 0.6 |
| [4] | Algeria (1) | 0.5 |
| [4] | Inner Mongolia (China) | 0.5 |
| [4] | Khalkha (Mongolia) | 0.5 |
| [4] | Shanghai (China) | 0.3 |
| [4] | Essen (German ) | 0.3 |
| [4] | Southern Han (China) | 0.2 |
| [4] | Shij. Tian. (Beijing, China) | 0.1 |
| [4] | Hakka (Taiwan) | 0.1 |
| Japan |  |
| Korea |  |
| Mongolia |  |
| Heilongjiang prov., China (Harbin city) |  |
References
[edit]- ↑ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
- ↑ Hildebrand WH, Domena JD, Parham P (1993). "Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8". Tissue Antigens. 41 (4): 190–5. doi:10.1111/j.1399-0039.1993.tb02001.x. PMID 8362411.
- ↑ derived from IMGT/HLA
- 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.