Flumedroxone

This article is about a non-clinically used progesterone derivative. For the pharmaceutical drug, see flumedroxone acetate.

Flumedroxone

Clinical data
Other names	17α-Hydroxy-6α-(trifluoromethyl)pregn-4-ene-3,20-dione; 6α-Trifluoromethyl-17α-hydroxyprogesterone
Identifiers
IUPAC name (2R,8S,14S,15S)-14-acetyl-14-hydroxy-2,15-dimethyl-8-(trifluoromethyl)tetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
CAS Number	15687-21-5 Y Acetate salt: 987-18-8 Y
PubChem CID	71881
ChemSpider	16736667
UNII	K80185F39X Acetate salt: S0S93EK936 Y
ChEMBL	ChEMBL2104932
CompTox Dashboard (EPA)	DTXSID40905080
Chemical and physical data
Formula	C22H29F3O3
Molar mass	398.466 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H](C4=CC(=O)CC[C@]34C)C(F)(F)F)C)O
InChI InChI=1S/C22H29F3O3/c1-12(26)21(28)9-6-16-14-11-18(22(23,24)25)17-10-13(27)4-7-19(17,2)15(14)5-8-20(16,21)3/h10,14-16,18,28H,4-9,11H2,1-3H3/t14-,15+,16+,18+,19-,20+,21+/m1/s1 Key:CDZJOBWKHSYNMO-SCUQKFFVSA-N
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Flumedroxone is a steroidal progestogen of the 17α-hydroxyprogesterone group that was never marketed. The C17α acetate ester of flumedroxone, flumedroxone acetate, has been marketed as an antimigraine drug.