ESCO1

ESCO1
Identifiers
Aliases	ESCO1, A930014I12Rik, CTF, ECO1, EFO1, ESO1, establishment of sister chromatid cohesion N-acetyltransferase 1
External IDs	OMIM: 609674; MGI: 1925055; HomoloGene: 62166; GeneCards: ESCO1; OMA:ESCO1 - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4MXE
Gene location (Human)
Chr.	Chromosome 18 (human)
End	21,600,884 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	10,610,352 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; tendon of biceps brachii; ; pancreatic epithelial cell; ; tibialis anterior muscle; ; secondary oocyte; ; Achilles tendon; ; deltoid muscle; ; testicle; ; gonad; ; epithelium of nasopharynx;
	Top expressed in
	saccule; ; zygote; ; primary oocyte; ; secondary oocyte; ; otic placode; ; otic vesicle; ; mesenteric lymph nodes; ; lacrimal gland; ; cumulus cell; ; olfactory epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; acyltransferase activity; metal ion binding; N-acetyltransferase activity; zinc ion binding; peptide-lysine-N-acetyltransferase activity; identical protein binding; acetyltransferase activity;
Cellular component	chromatin; nucleus; nucleoplasm; chromosome;
Biological process	post-translational protein acetylation; cell cycle; sister chromatid cohesion; regulation of DNA replication; peptidyl-lysine acetylation;
	Sources:Amigo / QuickGO
Orthologs
	114799
	77805
	ENSG00000141446
	ENSMUSG00000024293
	Q5FWF5
	Q69Z69
	NM_052911
	NM_001081222; NM_144542
	NP_443143
	NP_001074691
	Wikidata
View/Edit Human	View/Edit Mouse

Establishment of sister chromatid cohesion N-acetyltransferase 1 is a protein that in humans is encoded by the ESCO1 gene.^[5]

Function

ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion.^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000141446 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024293 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Establishment of sister chromatid cohesion N-acetyltransferase 1". Retrieved 2015-09-17.
↑ Hou F, Zou H (2005). "Two human orthologues of Eco1/Ctf7 acetyltransferases are both required for proper sister-chromatid cohesion". Molecular Biology of the Cell. 16 (8): 3908–18. doi:10.1091/mbc.E04-12-1063. PMC 1182326. PMID 15958495.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human N-acetyltransferase ESCO1

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 18 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000141446 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024293 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Establishment of sister chromatid cohesion N-acetyltransferase 1". Retrieved 2015-09-17.

[pmid15958495-6] Hou F, Zou H (2005). "Two human orthologues of Eco1/Ctf7 acetyltransferases are both required for proper sister-chromatid cohesion". Molecular Biology of the Cell. 16 (8): 3908–18. doi:10.1091/mbc.E04-12-1063. PMC 1182326. PMID 15958495.

[1]

[2]

[3]

[4]

[5]

[6]

This page was redesigned at the edge.

ESCO1

Function

See also

References

External links