Draft:Timothy Cover
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You have created enough articles now that you can do better. Remove hanging-chad spaces, sources go after punctuation, detail what are the awards (no grants), merge duplicate sources. Declined by Ldm1954 7 days ago. | |
Comment: Awards and Honors section is a bit broken, and Career is also unclear. Jishara (please ping upon response) (talk) 17:55, 16 September 2026 (UTC)
- Comment: In accordance with Wikipedia's Conflict of interest guideline, I disclose that I have a conflict of interest regarding the subject of this article. Mitchell2526 (talk) 17:36, 14 September 2026 (UTC)
Timothy Cover
[edit]Timothy L. Cover is an American physician-scientist and microbiologist. He is Professor of Medicine in the Division of Infectious Diseases and Professor of Pathology, Microbiology and Immunology at Vanderbilt University School of Medicine.[1] He is a member of the Vanderbilt Institute of Chemical Biology,[2] Vanderbilt Institute for Infection, Immunology, and Inflammation,[3] and the Vanderbilt-Ingram Cancer Center.[4]
Education and Career
[edit]Cover received his Bachelor of Science degree in Biology from Muhlenberg College.[5][6] In 1984, he received his Doctor of Medicine degree from Duke University School of Medicine.[7][6] Cover completed his residency training in Internal Medicine at Pennsylvania State University and fellowship training in Infectious Diseases at the University of Colorado and Vanderbilt University Medical Center.[5][6] Cover'c current title is Professor of Medicine in the Division of Infectious Diseases within the Department of Medicine at Vanderbilt University Medical Center and Professor of Pathology, Microbiology and Immunology.[1][8]
Research
[edit]Cover is an infectious disease specialist.[7] His laboratory researches the bacterium Helicobacter pylori and its role as a causative agent of Gastric cancer.[8][9]
To investigate molecular mechanisms by which H. pylori causes disease, Cover's laboratory uses a variety of molecular biology, cell biology, genomic, and immunologic methods. Current projects include investigation of two H. pylori toxins (VacA and CagA) in cell culture and animal models, investigation of the H. pylori type IV secretion system that delivers CagA into gastric epithelial cells, investigation of mechanisms by which gene expression is regulated in H. pylori, and comparative genome sequence analysis of H. pylori strains isolated from patients with different disease states, with the goal of identifying new bacterial biomarkers that predict the development of gastric cancer.[1]
Honors and awards
[edit]Cover’s honors and awards include
- Tennessee Valley Staff Physician Receives Award to Support Research on Stomach Bacteria,[9]
- American Society for Clinical Investigation,a nonprofit medical honor society for U.S. physician-scientists[1][10][11]
- Association of American Physicians, nonprofit, professional organization[12]
- American Academy of Microbiology, recognizes scientists for contributions to microbiology and provide microbiological expertise in the service of science and the public[13][14]
- American Association for the Advancement of Science, Advance science, engineering, and innovation throughout the world for the benefit of all. Advancing Science, Serving Society.[13][15]
Selected publications
[edit]- Cover, Timothy L.; Blaser, Martin J. (1992). "Purification and characterization of the vacuolating toxin from Helicobacter pylori". Journal of Biological Chemistry. 267 (15): 10570–10575. PMID 1587837.
- Atherton, John C.; Cao, Ping; Peek, Richard M. Jr.; Tummuru, Murali K. R.; Blaser, Martin J.; Cover, Timothy L. (1995). "Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori: association of specific vacA types with cytotoxin production and peptic ulceration". Journal of Biological Chemistry. 270 (30): 17771–17777. doi:10.1074/jbc.270.30.17771. PMID 7629077.
- Cover, Timothy L.; Blanke, Steven R. (2005). "Helicobacter pylori VacA, a paradigm for toxin multifunctionality". Nature Reviews Microbiology. 3 (4): 320–332. doi:10.1038/nrmicro1095. PMID 15759043.
- Cover, Timothy L.; Blaser, Martin J. (2009). "Helicobacter pylori in health and disease". Gastroenterology. 136 (6): 1863–1873. doi:10.1053/j.gastro.2009.01.073. PMID 19457415.
- Frick-Cheng, Arwen E.; Pyburn, Tasia M.; Voss, Bradley J.; McDonald, W. Hayes; Ohi, Melanie D.; Cover, Timothy L. (2016). "Molecular and structural analysis of the Helicobacter pylori cag type IV secretion system core complex". mBio. 7 (1): e02001-15. doi:10.1128/mBio.02001-15. PMID 26758182.
- Chung, Jeong Min; Sheedlo, Michael J.; Campbell, Anne M.; Sawhney, Neha; Frick-Cheng, Arwen E.; Lacy, Dana Borden; Cover, Timothy L.; Ohi, Melanie D. (2019). "Structure of the Helicobacter pylori Cag type IV secretion system". eLife. 8: e47644. doi:10.7554/eLife.47644. PMID 31210639.
- Lin, Aung Soe; McClain, Mark S.; Beckett, Amber C.; Caston, Rhonda R.; Harvey, M. Lorena; Dixon, Beverly R. E. A.; Campbell, Anne M.; Shuman, Jennifer H. B.; Sawhney, Neha; Delgado, Alberto G.; Loh, John T.; Piazuelo, M. Blanca; Algood, Holly M. Scott; Cover, Timothy L. (2020). "Temporal control of the Helicobacter pylori Cag type IV secretion system in a Mongolian gerbil model of gastric carcinogenesis". mBio. 11 (3): e01296-20. doi:10.1128/mBio.01296-20. PMID 32605987.
- McClain, Mark S.; Voss, Bradley J.; Cover, Timothy L. (2020). "Lipoprotein processing and sorting in Helicobacter pylori". mBio. 11 (3): e00911-20. doi:10.1128/mBio.00911-20. PMID 32430470.
References
[edit]- 1 2 3 4 "Timothy L. Cover, MD | Vanderbilt Institute for Infection, Immunology and Inflammation". www.vumc.org. Retrieved 2026-09-14.
- ↑ "Our Team". Vanderbilt University. Retrieved 2026-09-14.
- ↑ "Faculty | Vanderbilt Institute for Infection, Immunology and Inflammation". www.vumc.org. Retrieved 2026-09-14.
- ↑ "Member Search | Vanderbilt-Ingram Cancer Center". vicc.org. Retrieved 2026-09-14.
- 1 2 "Timothy Cover, M.D. | The Cover Lab". Retrieved 2026-09-14.
- 1 2 3 "Cover [1037] | Vanderbilt-Ingram Cancer Center". vicc.org. Retrieved 2026-09-14.
- 1 2 "Health. US News".
- 1 2 "Timothy Cover". Vanderbilt University. Retrieved 2026-09-14.
- 1 2 "Tennessee Valley Staff Physician Receives Award to Support Research on Stomach Bacteria | VA Tennessee Valley health care". Veterans Affairs. 2024-03-13. Retrieved 2026-09-14.
- ↑ "Dr. Timothy Cover, MD – Nashville, TN | Infectious Disease on Doximity". Doximity. Retrieved 2026-09-14.
- ↑ "ASCI". The American Society for Clinical Investigation. Retrieved 2026-09-14.
- ↑ MacMillan, Leigh (2015-06-11). "Medical societies honor VUMC's Cover, Williams". Vanderbilt Health News. Retrieved 2026-09-14.
- 1 2 "User Detail | Department of Medicine". medicine.vumc.org. Retrieved 2026-09-14.
- ↑ "American Academy of Microbiology". ASM. Retrieved 2026-09-16.
- ↑ "Mission and History | American Association for the Advancement of Science (AAAS)". American Association for the Advancement of Science (AAAS). Retrieved 2026-09-16.
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