Domiodol

Domiodol
Clinical data
Trade names	Mucolitico Maggioni
ATC code	R05CB08 (WHO) ;
Identifiers
	IUPAC name [2-(iodomethyl)-1,3-dioxolan-4-yl]methanol;
CAS Number	61869-07-6 ;
PubChem CID	43814;
DrugBank	DB13768 ;
ChemSpider	39887 ;
UNII	C1PXF8V06N;
KEGG	D03888 ;
ChEBI	CHEBI:134992;
ChEMBL	ChEMBL2106471;
CompTox Dashboard (EPA)	DTXSID20866887 ;
Chemical and physical data
Formula	C5H9IO3
Molar mass	244.028 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES ICC1OC(CO)CO1;
	InChI InChI=1S/C5H9IO3/c6-1-5-8-3-4(2-7)9-5/h4-5,7H,1-3H2 ; Key:NEIPZWZQHXCYDV-UHFFFAOYSA-N ;
	(verify)

Domiodol is a mucolytic and expectorant.^[1] It has been marketed in Italy by Maggioni under the trade name Mucolitico Maggioni and sold in syrup, sachet, and tablet form, with a dosage of 60mg three to four times daily in adults. Contraindications include severe renal or hepatic insufficiency.^[2]

References

↑ Kogi K, Konishi K, Saito T (1983). "Pharmacological and toxicological studies on domiodol, a new mucolytic agent and expectorant". Arzneimittel-Forschung. 33 (9): 1281–6. PMID 6685509.
↑ Schlesser JL (1991). Drugs Available Abroad, 1st Edition. Derwent Publications Ltd. p. 70. ISBN 0-8103-7177-4.

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[1] Kogi K, Konishi K, Saito T (1983). "Pharmacological and toxicological studies on domiodol, a new mucolytic agent and expectorant". Arzneimittel-Forschung. 33 (9): 1281–6. PMID 6685509.

[2] Schlesser JL (1991). Drugs Available Abroad, 1st Edition. Derwent Publications Ltd. p. 70. ISBN 0-8103-7177-4.

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References