Dimethyl phosphorochloridothioate
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| Preferred IUPAC name
O,S-Dimethyl phosphorochloridothioate | |
| Identifiers | |
3D model (JSmol) |
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CompTox Dashboard (EPA) |
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| Properties | |
| C2H6ClO2PS | |
| Molar mass | 160.55 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dimethyl phosphorochloridothioate is an organophosphate compound used as an intermediate for insecticides, pesticides, and fungicides, as well as additives for oil and gasoline, plasticizers corrosion inhibitors; flame retardants and flotation agents.[1] It is an irritant for skin, eyes, and mucous membranes.[2]
Uses
[edit]Dimethyl phosphorochloridothionate is used to synthesize the widely used and highly toxic insecticide Parathion by reacting it with sodium p-nitrophenate[3].
Dimethyl phosphorochloridothionate is also known to have been used to synthesize other organophosphate compounds such as O,O-dimethyl phosphoramidothioate [4], which is an intermediate used in producting other insecticides such as Acephate.[5]
References
[edit]- ↑ "DIMETHYL CHLOROTHIOPHOSPHATE | CAMEO Chemicals | NOAA". cameochemicals.noaa.gov. Retrieved 2026-07-04.
- ↑ "CompTox Chemicals Dashboard". comptox.epa.gov. Retrieved 2026-07-04.
- ↑ "Parathion | Medical Management Guidelines | Toxic Substance Portal | ATSDR". wwwn.cdc.gov. Retrieved 2026-07-04.
- ↑ US10669295B2, Prasad, Vic; Huang, David & KATARIA, Kamal et al., "Process for preparation of O,O-dimethyl phosphoramidothioate and N-(methoxy-methylsulfanylphosphoryl) acetamide", issued 2020-06-02
- ↑ WO2022180555A1, Wankhade, Atul; Shah, Pathik & SONAWANE, Praful et al., "A process for production of acephate", issued 2022-09-01
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