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Chemical castration

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From Wikipedia, the free encyclopedia

Syringe for Depo Provera (the Pfizer brand-name for depot medroxyprogesterone acetate). Medroxyprogesterone acetate is the medication specified in several states' legislation authorizing the chemical castration of sex offenders.

Chemical castration is castration via anaphrodisiac drugs, whether to reduce libido and sexual activity, to treat cancer, or otherwise. Unlike surgical castration, where the gonads are removed through an incision in the body,[1] chemical castration does not remove organs and is not a form of sterilization.[2]

Chemical castration is generally reversible when treatment is discontinued,[3] although permanent effects in body chemistry can sometimes be seen, as in the case of bone density loss increasing with length of use of depot medroxyprogesterone acetate (DMPA). In men, chemical castration reduces sex drive and the capacity for sexual arousal, side effects of some drugs may include depression, suicidal ideation, hot flashes, anemia, infertility, increase in body fat and higher risks of cardiovascular diseases and osteoporosis. In women, chemical castration acts by decreasing testosterone levels in order to lower their sex drive, side effects include the deflation of breast glands, expansion of the size of the nipple and shrinking of bone mass.[4]

Several papers have discussed studies of chemical castration as a treatment for paraphilic disorders and hypersexuality. These conditions (commonly diagnosed in sex offenders) are believed to contribute toward offenders' recidivism. Studies showed reduction of criminal behavior, with several critics arguing for bias in study design.[5][6][7][8] Medroxyprogesterone acetate-based drugs for this treatment remains an off-label use.[9]

In the 1990s and beyond, state legislatures in the United States of America have authorized prison and parole authorities to impose chemical castration (via DMPA or equivalent antiandrogen) as a condition of parole or supervised release for sex offenders (particularly those targeting children). The measures are adopted under pressure to deliver "law and order" policies. However, due process and medical ethics concerns led correctional officials in the states that authorized chemical castration in the 1990s to admit they rarely use this authority, with medroxyprogesterone acetate one of several potential psychopharmacological treatments offered to parole-eligible convicts before release.[10][11][12][13][14][15][16] Two states that first approved chemical castration in the 1990s (Oregon and Georgia) later revoked authorization.[17][18][19]

Effects

On males

When used on males, these drugs can reduce sex drive, sexual fantasies, and capacity for sexual arousal. Life-threatening side effects are rare, but some users show increases in body fat and reduced bone density, which increase long-term risk of cardiovascular disease and osteoporosis, respectively. Males may also experience gynecomastia (development of larger-than-normal mammary glands in males); full development is less common unless chemical castration is combined with feminizing estrogen therapy.[4]

Some drugs, such as medroxyprogesterone acetate, cyproterone acetate, and LHRH agonists can decrease serum testosterone and estradiol in the body, thus impairing the metabolism of glucose and lipid. These drugs can also cause depression, hot flashes, infertility, and anemia, aside from cardiovascular diseases and osteoporosis. The risk of side effects caused by chemical castration drugs can increase depending on the length of time under which they are administered.[20] A 2004 study in which eleven men were chemically castrated ended with one committing suicide after one year of treatment;[21] in another 2020 study, increases in suicidal ideations was reported by 8% of its treatment group, which led to the hospitalization of two of the 25 subjects who had been administered degarelix.[22][23]

On females

When used on females, the effects are similar, though there is little research about chemically lowering female's sex drive or female-specific anaphrodisiacs, since most research focuses on the opposite, but anti-androgenic hormone regimens would lower testosterone in females which can impact sex drive or sexual response.[24][25][26] These drugs also deflate the breast glands and expand the size of the nipple. Also seen is a sudden shrinking in bone mass and discoloration of the lips,[27][28] reduced body hair,[29] and muscle mass.[30]

As treatment for cancer

A major medical use of chemical castration is in the treatment of hormone-dependent cancers, such as prostate cancer, where it has largely replaced the practice of surgical castration. Chemical castration involves the administration of antiandrogen drugs, such as cyproterone acetate, flutamide, or gonadotropin-releasing hormone agonists.[31][32]

In 2020, a man in Canada who was receiving antiandrogen drug treatment for colon cancer murdered his doctor over the belief that he was being chemically castrated due to his race.[33]

As treatment for sex offenders

Various drugs (including both hormonal-based and psychoactive drugs) have been studied and used to treat sex offenders.

  • The first reported use of hormonally-based medications to reduce pathological sexual behavior occurred in 1944, when diethylstilbestrol was used with the purpose of lowering men's testosterone.[34]
  • Cyproterone acetate (CPA, trade name Androcur) was used in experiments to reduce the libido of sex offenders starting with Ursula and Leonhard Laschet of West Germany in the 1960s. By 1975, evidence suggested that the drug was tolerated with side effects of fatigue, gynecomastia, depression.[35] In comparison to drugs studied later for chemical castration, CPA has comparable effectiveness to medroxyprogesterone acetate in suppressing sexual urges and function but appears to be less effective than GnRH modulators like leuprorelin and has more side effects.[36] CPA is approved to treat abnormal sex drive in 20 countries, including Australia and the United Kingdom where it is a documented on-label use.[37][38][39] The European Medicines Agency advises that use of "should only be used for reduction of sex drive in sexual deviations in men when other treatment options are not suitable." This warning is for the small but serious side-effect risk of meningioma developing after cumulative doses.[40] Australia and the United Kingdom have issued similar warnings.[38][39]
  • The first experimental use of a depot injection to improve compliance with medications to curb sexual behavior is recorded in a 1973 study by Leopold H. Field of the United Kingdom, using antipsychotic agent benperidol (trade names Anquil, Frenactil) rather than a hormonal agent. Benperidol had previously been attempted for lowering libido in sex offenders, but nausea had prevented compliance in those taking the medication orally. The subjects were 28 sex-offenders who victimized children. Reported effects of the benperidol depot injection included "abolition of sexual desire and inability to obtain an erection either as the result of fantasy of masturbation".[41]
  • In 1981, in an experiment by Canadian Pierre Gagné, 48 males admitted to Sherbrooke Hospital with histories of criminal sexual behaviour were given injections of medroxyprogesterone acetate (MPA, or DMPA in depot injection, trade name Depo-Provera). Durations for the administration were up to twelve months with dosage levels tapered after four or five months. Forty of those subjects were recorded as having diminished desires for deviant sexual behaviour, as well as less frequent sexual fantasies and greater control over sexual urges. The research paper recorded a continuation of this improved behaviour after the administration of the drug had ended, with no evidence of adverse side effects, and so recommended medroxyprogesterone acetate along with counselling as a successful method of treatment for serial sex offenders.[5] Medroxyprogesterone acetate is the drug specifically named by legal codes of U.S. states with compulsory chemical castration.[42]
  • Leuprolide acetate (LA, a.k.a. leuprorelin and leuprolidetrade; trade names Lupron, Eligard, Lucrin, and Lupaneta) is an LHRH agonist used for chemical castration. The drug was originally used to treat advanced prostate cancer.[43][44] Studies of the drug for treatment of individual sex offenders are recorded as early as the 1990s, with larger scale studies starting in the 2000s.[45] This drug has been observed as having higher rates of success in reducing abnormal sexual urges and fantasies, but is often reserved for those offenders who are at a high risk of reoffending due to the drug's intense effects including the notable phenomenon known as the "flare", in which testosterone levels temporarily surge by approximately 50% within the first 1 to 2 weeks of therapy.[46][43]

Psychotherapy has also recently been used in conjunction with chemical castration in order to maximize and prolong the beneficial results.[47] Schober et al. reported in 2005 that when cognitive behavioral therapy combined with leuprolide acetetate was compared to cognitive behavioral therapy alone, the combination therapy produced a much more significant reduction of pedophilic fantasies and urges as well as masturbation.[48] Chemical castration therapy reduces an individual's libido which then makes some offenders more responsive to the introduction of psychotherapy.[49] This combination therapy is most often utilized in those who are at a high risk of offending.[47]

Scientific critique

Some criminologists argue that the lower recidivism rates seen in male sex offenders who undergo chemical castration might not be due to the medication's biological effects. Instead, one hypothesis is that men who agree to chemical castration — often in exchange for a shorter prison sentence — may simply be more motivated to stay out of prison than those who refuse the treatment. These men might also be more skilled at hiding any new offences, making it appear as though they reoffend less when they actually do not. Additionally, there could be investigation bias, in that police and parole officers might assume castrated men are less dangerous and therefore be less thorough when investigating them and thus causing a self-fulfilling prophecy (in the assumption that castrated men are less dangerous), which could artificially lower the apparent recidivism rate. Some criminologists even suggest that offenders may sell their prescribed medications on the black market, giving them extra income to fund ways to conceal their criminal behaviour more effectively than untreated offenders.[50][51][52]

Separately, some neurologists acknowledge that testosterone plays a role in sexual arousal but argue that simply lowering sex drive may not reduce inappropriate sexual behaviour. They explain that when internal sexual arousal signals are weaker (because of reduced testosterone), individuals may require stronger and more specific external stimuli to achieve satisfaction. This could make it harder for former offenders to manage their remaining sex drive through ordinary masturbation without pornography or other preferred stimuli. In other words, reducing sex drive biologically might inadvertently increase the need for risky or socially unacceptable outlets rather than solving the underlying behavioural problems.[8][53]

While chemical castration through anti-androgens may be viewed as uniquely providing retribution for sex offenses, incapacitation of offenders is possible by lowering their libido with psychiatric medication rather than anti-androgens. In the United Kingdom, a program offering treatment for sex offenders ("Medical Management of Problematic Sexual Arousal") evaluated groups of patients using the Sexual Compulsivity Scale (SCS), a psychometric score of libido shown to predict risky sexual behavior. Patients were divided into an unmedicated group, a group treated with anti-androgen cyproterone acetate (CPA), and another treated with selective serotonin reuptake inhibitor-class antidepressant drugs (including fluoxetine and sertraline). While medicated patients had lower SCS scores than unmedicated ones, the SSRI-treated group had lower scores than the CPA-treated group.[54] Guidelines for National Institute for Health and Care Excellence (NICE) note that fluoxetine is not licensed in the United Kingdom for the treatment of hypersexuality and use for this indication is off‑label.[55] As of 2026, a randomized controlled trial sponsored by Nottingham Trent University is underway to investigate and evaluate fluoxetine for this purpose ("Fluoxetine Assisted Sexual Arousal Reduction" or FASAR).[56]

Chemical castration for sex offenders by country

Africa

South Africa

In July 2022, a proposed policy of chemical castration for rapists was introduced at the national policy conference of the ruling party, the African National Congress, by the party's Women's League.[57]

Americas

Argentina

In March 2010, Guillermo Fontana of CNN reported that officials in Mendoza, a province in Argentina, approved the use of voluntary chemical castration for rapists, in return for reduced sentences.[58]

United States

In 1966, psychologist John Money became the first in the U.S. to employ chemical castration by prescribing medroxyprogesterone acetate (MPA) as a treatment for a "bisexual transvestite with pedophiliac homosexual incest" in treatment after their wife informed Money about them having sexually abused their 6-year-old son.[59] The drug has thereafter become a mainstay of chemical castration in the U.S. Despite having been extensively used in the U.S. for the purpose of decreasing sexual impulses, the drug has never been approved by the FDA for use as a treatment for sexual offenders.[34]

Legislation by state
Current state laws authorizing chemical castration for sex offenders in the United States of America
State Date enacted Authorizing legislation Codified law Applicable offenses Overseeing agencies Notes
Alabama 30 May 2019 Alabama Legislative Acts of 2019 # 522, authored by Steve Hurst[60] Parole of Persons Convicted of Sex Offense Involving Person Under 13 Years of Age - Chemical Castration Treatment, Title 15 Code of Alabama §15-22-27.4[61] Any sex offense (defined by Code of Alabama § 15-20A-5) "involving a person under the age of 13 years." Alabama Department of Public Health; Alabama Board of Pardons and Paroles "A parolee who intentionally stops receiving the treatment required under this section shall be guilty of a Class C felony."
California 18 September 1996 Chapter 596, Statutes of 1996, authored by William Hoge[42][62] Of Other and Miscellaneous Offenses, California Penal Code §645 Sex offenses against children under 13 years of age, including sodomy, molestation, or rape California Department of Corrections and Rehabilitation Regulations for implementing the measure are "reserved" in Title 15, California Code of Regulations § 3700, but no specific regulations were published.[63]
Florida 30 May 1997 1997 Florida Statutes Ch. 97-184, authored by Mark Ogles and Anna Cowin[64][65] Administration of medroxyprogesterone acetate (MPA) to persons convicted of sexual battery, Fla. Stat. § 794.0235 (1997) All offenses covered by Florida's sexual battery law (Fla. Stat. § 794.011 (2025)) Florida Department of Corrections Refusal to appear or allow administration is a "felony of the second degree."
Iowa 6 May 1998 Ch. 1171, Laws of the Seventy-Seventh G.A., 1998 Session, authored by Jeff Lamberti[66][67] Sex Offender Special Sentencing And Hormone Treatment, Iowa Code Ch. 903B[68] Sex offenses against children "twelve years of age or younger" Iowa Department of Corrections Those sentenced "shall be required to pay a reasonable fee to pay for the costs of providing the treatment."
Louisiana 25 June 2008 Louisiana Acts 2008, No. 441, authored by Nick Gautreaux[69][70] Administration of medroxyprogesterone acetate (MPA) to certain sex offenders, Title 14, Louisiana Revised Statutes §43.6[69] Aggravated or first degree rape; sexual battery where victim is under the age of thirteen; second degree sexual battery; molestation of a juvenile when the victim is under the age of thirteen; aggravated crime against nature Louisiana Department of Public Safety & Corrections
  • Use of "any drug or other substance to reverse the effects of the treatment" punishable as contempt of court
  • Refusal to appear or allow administration punishable by a sentence of three to five years
Montana 24 April 1997[71] Montana Laws of 1997, Ch. 334, authored by Deborah Kottel[72] Chemical Treatment Of Sex Offenders, Title 45 Montana Code Annotated 2025 §45-5-512[73] Sexual assault, sexual intercourse without consent, or incest with a victim aged 16 years or younger Montana Department of Corrections "Failure to continue treatment as ordered by the department of corrections constitutes a criminal contempt of court for failure to comply with the sentence, for which the sentencing court shall impose a term of incarceration without possibility of parole of not less than 10 years or more than 100 years."
Wisconsin 15 June 1998 1997 Wisconsin Act 284, authored by Dean Kaufert[74] Paroles from state prisons and house of correction, 2023-24 Wisconsin Statutes Ch.304.06 (1q) (b)[75] Sexual assault against children aged 13 years or younger Wisconsin Department of Corrections
  • Legislation mentions "antiandrogens" generally. Any use as a condition of parole is regulated under the Wisconsin Administrative Code.[76]
  • In practice, Wisconsin Department of Corrections states that antiandrogens are never imposed, and states that it offers "pharmacological treatment to qualifying individuals on supervision" but does not impose them.[12]

California was the first U.S. state to specify the use of chemical castration for repeat child molesters as a condition of their parole under Cal. Penal Code § 645 following the 1996 passage of AB 3339 introduced by Assembly Member Bill Hoge.[77][62] This law stipulates castration for anyone convicted of child molestation with a minor under 13 years of age if they are on parole after their second offense. According to the text of the law, offenders may not reject the intervention,[77][62][78][79] although they may elect surgical castration instead of ongoing DMPA injections.[80]

At least eight other states (Alabama, Florida, Georgia, Iowa, Louisiana, Montana, Oregon, and Wisconsin) adopted measures authorizing chemical castration before a parole.[34] Alabama was the most recent state to do so 2019.[81]

Rarity of use

Chemical castration generates considerable press coverage as legislatures debate and pass such measures. Following these measures' passage, there are few records of state courts or correctional agencies using chemical castration, with officials reporting only rare use. Two states have ended their chemical castration programs entirely.

  • In 2005, a Palm Beach Post review found that Florida's use of their chemical castration measure was limited to 15 offenders out of a population of 2,300.[82]
  • In 2006, the legislature of Georgia repealed the state's chemical castration measure in a package of reforms that otherwise increased penalties for sex offenses.[83][84]
  • In 2010 a spokesperson for the California Department of Corrections in 2010 was quoted by CBS San Diego as having "no information showing the program is actually being implemented on a widespread basis."[10]
  • In 2011, Oregon's legislature passed an emergency measure to abolish the chemical castration program, having been unable to staff it.[18][19]
  • A 2020 investigative report by KTVH "failed to discover whether the treatment has ever been court-ordered or used since its passage" in the state of Montana in 1997.[13]
  • A 2021 report by the Wisconsin Legislative Council (non-partisan research staff of the Wisconsin State Legislature) found no records of chemical castration's use in the state.[12]
  • In 2021, Alabama Department of Public Health told Alabama Daily News that they had never administered medication for chemical castration since it had been legalized in 2019. Writer Caroline Beck pointed out the state's chemical castration statute is may be moot: chemical castration is imposed as a condition of parole, but applies mainly to crimes for which convicts are ineligible for parole entirely.[14]
  • A 2024 Associated Press article on Louisiana's new adoption of surgical castration as punishment found that its chemical castration statute (passed over a decade before) had rarely been invoked.[15]
  • An April 2026 review of "red tape" regulations by the Iowa Department of Corrections reported that the "utilization rate is extremely low" for its hormonal intervention therapy measure on the books since 1998.[16]
Opposition

The American Civil Liberties Union of Florida opposes the administration of any drug that is dangerous or has significant irreversible effect as an alternative to incarceration; however, they do not oppose the use of antiandrogen drugs for sex offenders under carefully controlled circumstances as an alternative to incarceration.[85] Law professor John Stinneford has argued that chemical castration is a cruel and unusual punishment because it exerts control over the mind of sex offenders to render them incapable of sexual desire and subjects them to the physical changes caused by the hormones used.[86]

Some people have argued that, based on the 14th Amendment, the procedure fails to guarantee equal protection: although the laws mandating the treatment do so without respect to gender, the actual effect of the procedure disproportionately falls upon men.[34] In the case of voluntary statutes, the ability to give informed consent is also an issue; in 1984, the U.S. state of Michigan's court of appeals held that mandating chemical castration as a condition of probation was unlawful on the grounds that the drug medroxyprogesterone acetate had not yet gained acceptance as being safe and reliable and also due to the difficulty of obtaining informed consent under these circumstances.[34]

Offering criminals the option of chemical castration for a reduction in sentence is an example of compulsory sterilization, as it can leave a subject sterile if they are required to continue treatment for more than 3 years.[87]

Asia

India

After the outrage following the gang rape of a woman in Delhi, the Government has submitted a draft proposing chemical castration along with an imprisonment of up to 30 years for rape convicts as part of the anti-rape law in India. The ministry is preparing a detailed bill and the recommended changes are under review.[88][89] Government is also planning to re-define the Juvenile Act and lower their age. One of the accused in the rape case was a juvenile and aged a few months less than 18 years. A view has been expressed by a section that only those below 15 years should be described as juvenile.[90][91]

Indonesia

In 2016, the Indonesian President Joko Widodo introduced a presidential regulation (Government Regulation in Lieu of Law No.1/2016) to allow chemical castration to be handed down as a punishment to child sex offenders. The regulation alters the contents of the 2002 Law on Child Protection (Law No. 23 of 2002).[92] DPR later enacted the regulation and amended the law (Law No. 17 of 2016) to enable chemical castration.[93] Although, a convicted child sex offender convicted in 2019 and eligible to be castrated chemically, the technical details on how the punishment will be carried out was under debate between the Government and Indonesian Physicians Association, resulting the sentence suspended until the technical details made.[94] On 7 December 2020, government finally issued Government Regulation No. 70/2020, that detailing technical details on how chemical castration carried out. The chemical castration punishment carried by specifically appointed physician in central government-run or local government-run hospital, and witnessed by witnesses from Attorney General, Ministry of Law and Human Rights, Ministry of Social Affairs, and Ministry of Health. The drugs used for the sentence however, not declared in the government regulation. The government regulation also authorized Ministry of Law and Human Rights to issue regulation to notify the Attorney General, and Ministry of Health to compile the technical procedure for the clinical assessment, conclusion, and implementation.[95]

Israel

In May 2009, two brothers from Haifa—convicted child molesters—agreed to undergo chemical castration to avoid committing further crimes.[96]

Pakistan

In 2020, Pakistan's Prime Minister Imran Khan told a journalist that he would prefer that rapists and child molesters be publicly hanged, but he added that, because he imagined that such capital punishment would gain negative attention for Pakistan on the international stage, he would instead like such offenders to "undergo chemical castration, or surgery be performed so they cannot do anything in future."[97] The Anti-Rape Ordinance 2020, approved by President Arif Alvi in December 2020,[98] allows for chemical castration of rapists without the consent of the offender.[99] Lawmakers gave it permanent approval in November 2021.[100]

South Korea

In July 2011, South Korea enacted a law allowing judges the power to sentence sex offenders who have attacked children under the age of 16 to chemical castration.[101] The law also allows for chemical castration to be ordered by a Ministry of Justice committee. On 23 May 2012, a serial sex offender legally called Park in the court case was ordered by the committee to undergo this treatment after his most recent attempted offense. On 3 January 2013, a South Korean court sentenced a 31-year-old man to 15 years in jail and chemical castration, the country's first-ever chemical castration sentence.[102][103]

Europe

Legislation allowing chemical castration exists in France, the United Kingdom, Poland, Russia, North Macedonia, Belgium and Turkey.[104]: 16  The drug cyproterone acetate has been commonly used for chemical castration throughout Europe. It resembles the drug MPA used in the U.S.[34]

Estonia

On 5 June 2012, Estonia passed a law that allows voluntary chemical castration as a part of complex treatment for less serious sex offenders as an alternative of imprisonment. However, the treatment is rarely used in practice.[105]

Germany

In the 1960s, German physicians used antiandrogens as a treatment for sexual paraphilia.[34]

Moldova

On 6 March 2012, Moldova legislated forcible chemical castration of child molesters; the law came into effect on 1 July 2012.[106]

North Macedonia

In October and November 2013, North Macedonia authorities were working on developing a legal framework and standard procedure for implementation of chemical castration that would be used for convicted child molesters. The castration is intended to be voluntarily, where as for the child molesters that repeat the criminal act it should be mandatory.[107]

Poland

On 25 September 2009, Poland legislated forcible chemical castration of child molesters.[108] This law came into effect on 9 June 2010; therefore in Poland "anyone guilty of raping a child under the age of 15 can now be forced to submit to chemical and psychological therapy to reduce sex drive at the end of a prison term".[109]

Portugal

In 2008, an experimental intervention program was launched in three Portuguese prisons: Carregueira (Belas, Sintra), Paços de Ferreira and Funchal. The program developers note the voluntary nature of the program a crucial factor in its success. They initially planned to cover ten inmates per prison, contemplating a possible enlargement to other prisons in the future. The program also included a rehabilitation component.[110]

In 2021, the right-wing populist Chega party pushed for a chemical castration bill in parliament.[111]

Russia

In October 2011, the Russian parliament approved a law that allows a court-requested forensic psychiatrist to prescribe the chemical castration of convicted sex offenders who have harmed children under the age of 14. The measure passed, allowing for chemical castration with the offender's consent.[112]

United Kingdom

Cyproterone acetate is available in the UK as Androcur-50 which is "indicated for the control of libido in men with severe hypersexuality or sexual deviation".[113]

A three year trial of voluntary chemical castration was introduced in the UK in 2007 by then home secretary John Reid.[114]

On 30 April 2010, a 30-year-old man in the United Kingdom found guilty of attempting to murder a 60-year-old woman, in order to abduct and rape her two granddaughters (aged eight and two), agreed to undergo chemical castration as part of the terms of his sentence. He was jailed for a minimum of 10 years at the High Court in Glasgow.[115]

"Medical Management of Problematic Sexual Arousal" (MMPSA), a joint program of HM Prison and Probation Service (HMPPS) and NHS England began in a limited number of prisons in England and Wales in 2009. The development of the program through 2025 in England and Wales was described in full in a paper published in the journal Criminal Behaviour and Mental Health.[116] The participants in MMPSA included three groups: non-medicated individuals, individuals provided with anti-androgen drugs, and individuals provided selective serotonin reuptake inhibitor antidepressant drugs. Comparisons of the three groups using the Sexual Compulsivity Scale (SCS) found greater that "over a 3‐month period, mean scores on the SCS dropped by 29.5% for men prescribed anti‐androgens and by 31.4% for those taking SSRIs, whereas no significant change was observed in the non‐medicated comparison group."[116][117]

In 2025, justice secretary Shabana Mahmood received international attention for announcing that chemical castration would roll out regionally across Britain as a pilot with voluntary participants, and that she was "exploring" if it could be made mandatory.[118][119] These statements were followed by the 2025 British cabinet reshuffle in which Mahmood was appointed Home Secretary.[120] Later that year, successor justice secretary David Lammy deposited documentation of research and conclusions about the MMPSA program. The document explicitly disclaimed any connection of the program to chemical castration.[121] Lammy and the Ministry of Justice subsequently made a press release announcing that more sex offenders would be offered "chemical suppressants" (including both SSRIs and anti-androgens) to lower libido, but the press release made no mention of chemical castration.[122]

The case of Alan Turing

In the United Kingdom, computer scientist Alan Turing, famous for his contributions to mathematics and computer science, pleaded guilty in 1952 to a charge of gross indecency for engaging in homosexual acts and accepted chemical castration as a term of his probation, thus avoiding imprisonment.[123] At the time, homosexual acts between males were illegal and homosexual orientation was widely considered to be a mental illness that could be treated with chemical castration.[123] Turing experienced side effects such as gynecomastia (breast enlargement)[124] and bloating of the physique.[123] He died two years later, with the inquest returning a verdict of suicide.[125] In 2009 British Prime Minister Gordon Brown issued a public apology for the "appalling" treatment of Turing after an online petition gained 30,000 signatures and international recognition.[126] He was given a posthumous Royal Pardon in December 2013.

Oceania

Australia

Use of cyproterone acetate to "reduce abnormal sex drive" is documented by the Australian Commission on Safety and Quality in Health Care.[38]

In 2010, a 58-year-old repeat child sex offender who had been subject to chemical castration was accused of inappropriately touching and kissing a seven-year-old young girl. He was found not guilty by a jury, which was not informed of the context of his previous offenses.[127]

New Zealand

In New Zealand, the antilibidinal drug cyproterone acetate is sold under the name Androcur. In November 2000 convicted child sex offender Robert Jason Dittmer attacked a victim while on the drug. In 2009 a study into the effectiveness of the drug by Dr David Wales for the Corrections Department found that no research had been conducted in New Zealand into the effectiveness and such trials were "ethically and practically very difficult to carry out."[128]

See also

References

  1. ↑ "Can Castration Be a Solution for Sex Offenders? Man Who Mutilated Himself in Jail Thinks So, but Debate on Its Effectiveness Continues in Va., Elsewhere" by Candace Rondeaux for the Washington Post, July 5, 2006
  2. ↑ Meisenkothen, Christopher (1999). "Chemical Castration — Breaking the Cycle of Paraphiliac Recidivism". Social Justice. 26 (1): 139–154. JSTOR 29767116.
  3. ↑ "Chemical Castration". mymcleveland.org.
  4. 1 2 Kanhai, Robert C.J.; Hage, J. Joris; van Diest, Paul J.; Bloemena, Elisabeth; Mulder, J. Wiebe (January 2000). "Short-Term and Long-Term Histologic Effects of Castration and Estrogen Treatment on Breast Tissue of 14 Male-to-Female Transsexuals in Comparison With Two Chemically Castrated Men". The American Journal of Surgical Pathology. 24 (1): 74–80. doi:10.1097/00000478-200001000-00009. PMID 10632490. S2CID 37752666.
  5. 1 2 Gagné, Pierre (May 1981). "Treatment of sex offenders with medroxyprogesterone acetate". American Journal of Psychiatry. 138 (5): 644–646. doi:10.1176/ajp.138.5.644. PMID 6453536.
  6. ↑ Berlin, F. S.; Meinecke, C. F. (May 1981). "Treatment of sex offenders with antiandrogenic medication: conceptualization, review of treatment modalities, and preliminary findings". American Journal of Psychiatry. 138 (5). American Psychiatric Publishing: 601–607. doi:10.1176/ajp.138.5.601. PMID 6453535.
  7. ↑ Cooper, Alan J. (1 February 1986). "Progestogens in the Treatment of Male Sex Offenders: A Review". The Canadian Journal of Psychiatry. 31 (1). SAGE Publications Inc: 73–79. doi:10.1177/070674378603100116. ISSN 0706-7437. PMID 2936441.
  8. 1 2 Berridge, Kent C.; Kringelbach, Morten L. (May 2015). "Pleasure Systems in the Brain". Neuron. 86 (3): 646–664. doi:10.1016/j.neuron.2015.02.018. PMC 4425246. PMID 25950633.
  9. ↑ Fitzgerald, Edward A. (1990–1991). "Chemical Castration: MPA Treatment of the Sexual Offender". American Journal of Criminal Law. 18 (1): 1–60. PMID 15991431.
  10. 1 2 "California law mandates chemical castration of certain offenders". CBS 8 San Diego. 6 May 2010.
  11. ↑ Cooper, Wilbert L. (21 June 2025). "These States Are Debating Castration for Sex Crimes. Experts Call It Cruel and Pointless". The Marshall Project. Retrieved 5 September 2026.
  12. 1 2 3 Bender-Olson, Katie (23 March 2021). "SEX OFFENDER RESTRICTIONS AND REQUIREMENTS". Wisconsin State Legislature. Wisconsin Legislative Council.
  13. 1 2 Schultz, Evelyn (2 March 2020). "MTN Investigates: Montana's chemical castration law". KTVH. Retrieved 5 September 2026.
  14. 1 2 Beck, Caroline (16 June 2021). "Chemical castration law hasn't been used since 2019 enactment". Alabama Daily News. Retrieved 5 September 2026.
  15. 1 2 Cline, Sara (3 June 2024). "Louisiana lawmakers approve surgical castration option for those guilty of sex crimes against children". www.pbs.org. Associated Press. Retrieved 5 September 2026.
  16. 1 2 "Red Tape Review Rule Report (Due: September 1, 2026". Iowa.gov. Iowa Department of Corrections. 29 April 2026.
  17. ↑ Konan, March (1 December 2006). "Georgia Sex Offender Act and National Sex Offender Laws". Law Library Student-Authored Works.
  18. 1 2 "Chapter 0419". www.oregonlegislature.gov. Retrieved 5 September 2026.
  19. 1 2 "76th OREGON LEGISLATIVE ASSEMBLY – 2011 Regular Session, MEASURE: SB 356 A – STAFF MEASURE SUMMARY – CARRIER: Sen. Whitsett". 23 March 2011. In 1999, the Legislative Assembly authorized the Oregon Department of Corrections (DOC) to establish a sex offender treatment program involving treating sex offenders with hormones such as medroxyprogesterone acetate, also known as Depo-Provera, for the purposes of diminishing the offender's sex drive. Since April of last year, the DOC has been unable to find anyone willing to provide the medical services needed to operate this program
  20. ↑ Lee, J. Y.; Cho, K. S. (2013). "Chemical Castration for Sexual Offenders: Physicians' Views". Journal of Korean Medical Science. 28 (2): 171–172. doi:10.3346/jkms.2013.28.2.171. PMC 3565125. PMID 23401647.
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  29. ↑ "Antiandrogen Drugs". TheFreeDictionary.com.
  30. ↑ Can drugs help sex offenders? by Clare Murphy for the BBC, 13 June 2007
  31. ↑ "About hormone therapy for prostate cancer". cancerresearchuk.org. 30 August 2017. Archived from the original on 17 November 2012. Retrieved 23 April 2014.
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  37. ↑ Assumpção AA, Garcia FD, Garcia HD, Bradford JM, Thibaut F (June 2014). "Pharmacologic treatment of paraphilias". The Psychiatric Clinics of North America. 37 (2): 173–181. doi:10.1016/j.psc.2014.03.002. PMID 24877704.
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  41. ↑ Field, Leopold H. (1 July 1973). "Benperidol in the Treatment of Sexual Offenders". Medicine, Science and the Law. 13 (3). SAGE Publications: 195–196. doi:10.1177/002580247301300306. ISSN 0025-8024. PMID 4729109.
  42. 1 2 "Statutes of California and Digests of Measures 1996, Volume 2" (PDF). California State Assembly, Office of the Clerk.
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  44. ↑ Silvani, Mauro; Mondaini, Nicola; Zucchi, Alessandro (30 September 2015). "Androgen deprivation therapy (castration therapy) and pedophilia: What's new". Archivio Italiano di Urologia e Andrologia. 87 (3): 222–6. doi:10.4081/aiua.2015.3.222. hdl:11568/1073189. PMID 26428645.
  45. ↑ Krueger, Richard B.; Kaplan, Meg S. (August 2001). "Depot-Leuprolide Acetate for Treatment of Paraphilias: A Report of Twelve Cases". Archives of Sexual Behavior. 30 (4): 409–422. doi:10.1023/A:1010213432606. ISSN 0004-0002. PMID 11446201.
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  49. ↑ Garcia, Frederico Duarte; Delavenne, Heloise Garcia; Assumpção, Alessandra de Fátima Almeida; Thibaut, Florence (10 April 2013). "Pharmacologic Treatment of Sex Offenders With Paraphilic Disorder". Current Psychiatry Reports. 15 (5): 356. doi:10.1007/s11920-013-0356-5. PMID 23572328. S2CID 11940516.
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  58. ↑ Fontana, Guillermo (20 March 2010). "Argentina province OKs chemical castration for rapists". CNN.
  59. ↑ Money, John (August 1970). "Use of an Androgen-Depleting Hormone in the treatment of male sex offenders∗". The Journal of Sex Research. 6 (3): 165–172. doi:10.1080/00224497009550662. ISSN 0022-4499.
  60. ↑ "ACT NUMBER 2019 - 522". Alabama Secretary of State. Legislative Acts. Retrieved 4 September 2026.
  61. ↑ "Alabama Legislature". alison.legislature.state.al.us. Retrieved 4 September 2026.
  62. 1 2 3 "California child molesters could face chemical castration". CNN. 29 August 1996. Archived from the original on 20 October 2006. Retrieved 23 November 2006.
  63. ↑ "Cal. Code Regs. Tit. 15, § 3700 - Medroxyprogesterone Acetate Treatment Program. [Reserved]". LII / Legal Information Institute. Retrieved 4 September 2026.
  64. ↑ Spalding, Larry (1 January 1998). "Florida's 1997 Chemical Castration Law: A Return to the Dark Ages". Florida State University Law Review. 25 (2): 117–139. ISSN 0096-3070.
  65. ↑ "Castration-bill worries fall on impatient ears". The Orlando Sentinel. 26 February 1997. p. 33. Retrieved 6 September 2026.
  66. ↑ "CHAPTER 1171 LAWS OF THE SEVENTY-SEVENTH G.A., 1998 SESSION : CONFINEMENT AND TREATMENT OF SEX OFFENDERS" (PDF). Iowa Legislature.
  67. ↑ "Chemical castration bill passes House". Iowa City Press-Citizen. 15 April 1998. p. 4. Retrieved 6 September 2026.
  68. ↑ "Iowa Code 903B.10 Hormonal intervention therapy — certain sex offenses". Iowa Legislature. Retrieved 31 August 2026.
  69. 1 2 "Louisiana Laws - Louisiana State Legislature". legis.la.gov. Retrieved 4 September 2026.
  70. ↑ "Jindal signs chemical castration bill, authorizing the castration of sex offenders in Louisiana". Abbeville Meridional. 26 June 2008. p. 12. Retrieved 6 September 2026.
  71. ↑ "'Chemical castration' OK'd for Montana inmates". New Bedford Standard-Times. 27 April 1997. Retrieved 4 September 2026.
  72. ↑ "Chemical castration bill drawing attention". The Independent-Record. 18 May 1997. p. 2. Retrieved 6 September 2026.
  73. ↑ "45-5-512. Chemical treatment of sex offenders, MCA". mca.legmt.gov. Retrieved 4 September 2026.
  74. ↑ "'Chemical castration' bill OK'd by Assembly". The Sheboygan Press. 13 February 1998. p. 4. Retrieved 6 September 2026.
  75. ↑ "Wisconsin Legislature: 304.06(1q)(b)". docs.legis.wisconsin.gov. Retrieved 6 September 2026.
  76. ↑ "Wisconsin Legislature: Ch. DOC 330 Title". docs.legis.wisconsin.gov. Retrieved 4 September 2026.
  77. 1 2 "XII. SEX OFFENDERS: Children and minors". California State Senate. Archived from the original on 22 March 2005. Retrieved 23 November 2006. The web page notes the Chemical Castration clause as a repeal and an addition to Section 645.
  78. ↑ "Codes Display Text". leginfo.legislature.ca.gov. Retrieved 17 June 2018.
  79. ↑ Macready, N. (21 September 1996). "Chemical castration for paedophiles approved". BMJ. 313 (7059): 707. doi:10.1136/bmj.313.7059.707a. PMID 8819434. S2CID 10395767.
  80. ↑ Panati, Charles (1998). Sexy Origins and Intimate Things: The Rites and Rituals of Straights, Gays, Bi's, Drags, Trans, Virgins, and Others. New York: Penguin. p. 483.
  81. ↑ "Alabama becomes seventh state to approve castration for some sex offenses". NBC News. 11 June 2019. Retrieved 11 June 2019.
  82. ↑ "Statute not clear on definition of 'appropriate candidate'". The Palm Beach Post. 30 August 2005. p. 18. Retrieved 5 September 2026.
  83. ↑ Konan, March (1 December 2006). "Georgia Sex Offender Act and National Sex Offender Laws". Law Library Student-Authored Works.
  84. ↑ "Georgia General Assembly". www.legis.ga.gov. Retrieved 31 August 2026.
  85. ↑ Spalding, Larry Helm (Winter 1998). "Florida's 1997 Chemical Castration Law: A Return to the Dark Ages". Florida State University Law Review. 25 (117): 124. Archived from the original on 17 September 2017. Retrieved 15 March 2016. Furthermore, the ACLU of Florida opposes any attempt to offer a defendant the opportunity to avoid incarceration by taking a drug that is dangerous or that has a significant irreversible effect on an individual's cognitive capacity or an important physical function, such as the ability to conceive children. The ACLU of Florida does not oppose the use of antiandrogen drugs under certain controlled circumstances as an alternative to incarceration for convicted sex offenders. Because the ACLU of Florida respects individual autonomy and supports the principle that punishment should be no more restrictive of liberty than necessary, an individual's choice of whether to accept an antiandrogen drug is entitled to considerable respect. In addition, because this choice arises in the inherently coercive context of sentencing, and because of the capacity for abuse of this sentencing option, such treatment should be available only under the most carefully controlled circumstances.
  86. ↑ Stinneford, John F. (20 July 2006). "Incapacitation through Maiming: Chemical Castration, the Eighth Amendment, and the Denial of Human Dignity". University of St. Thomas Law Journal (6–25). SSRN 918271.
  87. ↑ Ginzberg, Janet (1 March 1992). "Compulsory Contraception as a Condition of Probation: The Use and Abuse of Norplant". Brooklyn Law Review. 58 (3): 979. ISSN 0007-2362.
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  91. ↑ Dhingra, Sanya (4 May 2018). "PMO asks Women & Child ministry to examine demand for chemical castration of child rapists". ThePrint. Retrieved 24 November 2020.
  92. ↑ Cochrane, Joe (25 May 2016). "Indonesia Approves Castration for Sex Offenders Who Prey on Children". The New York Times. ISSN 0362-4331. Retrieved 26 May 2016.
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  97. ↑ Raja, Adeel (16 September 2020). "Pakistan's Prime Minister Imran Khan calls for chemical castration of those convicted of rape". CNN. Retrieved 16 September 2020.
  98. ↑ "Pakistan: Cruel and inhuman chemical castration punishment will not fix flawed system". Amnesty International. 16 December 2020. Retrieved 19 November 2021.
  99. ↑ Asad, Malik (16 December 2020). "Ordinance allowing castration of rapists approved". Dawn. President Dr Arif Alvi on Tuesday accorded approval to the Anti-Rape Ordinance 2020 which will ensure speedy trial of rape cases with women and children as victims and also allow for chemical castration of those convicted of such offences. However, contrary to the draft approved by the Cabinet Committee on Legislative Cases (CCLC), the consent of the convict will not be required for carrying out castration, but it will be the discretion of the judge of the trial court.
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  106. ↑ "Moldova will punish pedophiles with chemical castration". Noi.md. Archived from the original on 15 March 2012.
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  108. ↑ "Poland okays forcible castration for pedophiles". Reuters. 25 September 2009.
  109. ↑ "Poland approves chemical castration for paedophiles". ABC News. 8 June 2010. Archived from the original on 11 June 2010.
  110. ↑ "Mais condenações por abuso sexual de menor". Diário de Notícias. 5 October 2011. Archived from the original on 28 September 2013.
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  112. ↑ Times, The Moscow (9 February 2012). "Voluntary Chemical Castration For Sex Offenders Is Approved". The Moscow Times. Retrieved 6 September 2026.
  113. ↑ "High-dose cyproterone acetate: potential risk of (multiple) meningiomas". GOV.UK. Retrieved 6 September 2026.
  114. ↑ Curtis, Polly (13 March 2012). "Should sex offenders be chemically 'castrated'?". The Guardian. Retrieved 29 December 2020.
  115. ↑ "BBC News - 'Menace' jailed over child rape and abduction attempt". bbc.co.uk. 30 April 2010.
  116. 1 2 Winder, Belinda; Grubin, D.; Underwood, M.; Antoniadis, Z.; Carvalheiro, M.; Marshall, E.; Norman, C.; Bourne, R.; Kaul, A. (April 2026). "Medical Management of Problematic Sexual Arousal for People With a Sexual Conviction in England and Wales: Challenges, Learning and Progress". Criminal Behaviour and Mental Health: CBMH. 36 (2): 79–86. doi:10.1002/cbm.70030. ISSN 1471-2857. PMC 13063213. PMID 41863425.
  117. ↑ Winder, Belinda; Norman, Christine; Hamilton, Jackie; Cass, Steven; Lambert, Alex; Tovey, Laura; Hocken, Kerensa; Marshall, Emma; Lievesley, Rebecca; Hamilton, Laura; Antoniadis, Zoe; Kaul, Adarsh (3 May 2024). "Evaluation of selective-serotonin reuptake inhibitors and anti-androgens to manage sexual compulsivity in individuals serving a custodial sentence for a sexual offence". The Journal of Forensic Psychiatry & Psychology. 35 (3). Routledge: 425–460. doi:10.1080/14789949.2024.2338917. ISSN 1478-9949.
  118. ↑ "UK will roll out chemical castration for sex offenders". CNN. Associated Press. 22 May 2025. Retrieved 22 May 2025.
  119. ↑ "Sex offender chemical castration pilot expands to northern England". www.bbc.com. 16 September 2025. Retrieved 6 September 2026.
  120. ↑ "Ministerial appointments: September 2025". GOV.UK. 16 September 2025. Retrieved 7 September 2026.
  121. ↑ Lammy, David (24 September 2025). "Summary of the evidence on Medications to Manage Problematic Sexual Arousal and their impact on reoffending". Parliament.uk. Some states in the USA (including California, Florida and Alabama) also have 'chemical castration' laws (an umbrella term which refers to MMPSA does not amount to).
  122. ↑ "More sex offenders given chemical suppressants". GOV.UK. 18 September 2025. Retrieved 6 September 2026.
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  125. ↑ Thousands call for Turing apology, BBC, 31 August 2009
  126. ↑ "[ARCHIVED CONTENT] Treatment of Alan Turing was "appalling" – PM - Number10.gov.uk". nationalarchives.gov.uk. Archived from the original on 12 September 2009.
  127. ↑ Roanne Johnson (30 October 2010). "Convicted paedophile allowed to look after kids". Townsville Bulletin. Archived from the original on 19 May 2011.
  128. ↑ Francis, Clio (11 July 2011). "Chemicals don't always stop sex offenders". The Dominion Post. Retrieved 23 September 2011.

Further reading

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