Cefoselis

Cefoselis
Names
	IUPAC name (6R,7R)-3-[[3-amino-2-(2-hydroxyethyl)pyrazol-1-ium-1-yl]methyl]-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
	Other names Wincef
Identifiers
CAS Number	122841-10-5 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL2105940 ;
ChemSpider	16736411 ;
PubChem CID	5748845;
UNII	0B50MLU3H1 ;
CompTox Dashboard (EPA)	DTXSID3048285 ;
	InChI InChI=1S/C19H22N8O6S2/c1-33-24-12(10-8-35-19(21)22-10)15(29)23-13-16(30)27-14(18(31)32)9(7-34-17(13)27)6-25-3-2-11(20)26(25)4-5-28/h2-3,8,13,17,20,28H,4-7H2,1H3,(H4,21,22,23,29,31,32)/b24-12-/t13-,17-/m1/s1 Key: BHXLLRXDAYEMPP-SBGRAJFYSA-N ; InChI=1/C19H22N8O6S2/c1-33-24-12(10-8-35-19(21)22-10)15(29)23-13-16(30)27-14(18(31)32)9(7-34-17(13)27)6-25-3-2-11(20)26(25)4-5-28/h2-3,8,13,17,20,28H,4-7H2,1H3,(H4,21,22,23,29,31,32)/b24-12-/t13-,17-/m1/s1 Key: BHXLLRXDAYEMPP-SBGRAJFYBO;
	SMILES CO/N=C(\C1=CSC(=N1)N)/C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC=C(N4CCO)N)C(=O)[O-];
Properties
Chemical formula	C19H22N8O6S2
Molar mass	522.55 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Cefoselis is a fourth generation cephalosporin. It is used extensively in Japan and China in the clinical treatment of various gram positive and gram negative infections. A 2014 study illustrated that Cefoselis is effective at treating respiratory and urinary tract infections.^[1]

References

↑ Y.-B. Liu, X.-J. Lv, R.-J. Yu, H.-M. Qiu, J.-L. Bai, N. Jiang, J.-M. Lin, Y.-J. Liu, H.-Y. Yan, S.-D. Song, P. He, D.-Y. Guo, X.-S. Li (2014). "Multicenter, double-blind, randomized clinical trial of parenterally administered Cefoselis versus Cefepime for the treatment of acute bacterial infections". Eur Rev Med Pharmacol Sci. 18 (14): 2006–2012.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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[1] Y.-B. Liu, X.-J. Lv, R.-J. Yu, H.-M. Qiu, J.-L. Bai, N. Jiang, J.-M. Lin, Y.-J. Liu, H.-Y. Yan, S.-D. Song, P. He, D.-Y. Guo, X.-S. Li (2014). "Multicenter, double-blind, randomized clinical trial of parenterally administered Cefoselis versus Cefepime for the treatment of acute bacterial infections". Eur Rev Med Pharmacol Sci. 18 (14): 2006–2012.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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References